Reptile · Python regius · typical adult weight 1.00–2.00 kg
Cimetidine is dosed at 4 mg/kg PO, IM q8-12h in ball pythons, per Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.272 (2026-08-01, PENDING REVIEW). Cimetidine is used in ball pythons for Gastric and duodenal ulceration; esophagitis; gastroesophageal reflux. Routes documented in ball pythons: PO, IM. A typical adult ball python weighs 1.00–2.00 kg. ExoticRx lists 1 cited dose rule for Cimetidine in ball pythons, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tagamet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO, IM | 4 mg/kg | q8-12h | Gastric and duodenal ulceration; esophagitis; gastroesophageal reflux | Weak | Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.272 (2026-08-01, PENDING REVIEW) |
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Competitively blocks histamine H2 receptors on parietal cells, reducing basal and stimulated gastric acid secretion.
Inhibits cytochrome P450 enzymes (many drug interactions — theophylline, benzodiazepines, etc.). Less potent than famotidine. Gynecomastia with chronic use in humans. Give 30 min before meals.
Species-specific contraindications and adverse-reaction reports for ball pythons may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cimetidine dose range in ball pythons, with cited source references: PO, IM 4 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cimetidine in ball pythons: PO, IM.
Cimetidine is indicated in ball pythons for: Gastric and duodenal ulceration; esophagitis; gastroesophageal reflux.
These are general warnings for Cimetidine across species; consult the ball python dosing table above for species-specific guidance. Inhibits cytochrome P450 enzymes (many drug interactions — theophylline, benzodiazepines, etc.). Less potent than famotidine. Gynecomastia with chronic use in humans. Give 30 min before meals.
Why a species-specific page? Cimetidine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in ball pythons — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.