Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Cimetidine is dosed at 4 mg/kg PO, IM q8-12h in eastern box turtles, per 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1419 (2026-08-01, PENDING REVIEW). Cimetidine is used in eastern box turtles for gastric and duodenal ulceration; oesophagitis; gastro-oesophageal reflux. Routes documented in eastern box turtles: PO, IM. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Cimetidine in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tagamet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO, IM | 4 mg/kg | q8-12h | gastric and duodenal ulceration; oesophagitis; gastro-oesophageal reflux | Weak | 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1419 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitively blocks histamine H2 receptors on parietal cells, reducing basal and stimulated gastric acid secretion.
Inhibits cytochrome P450 enzymes (many drug interactions — theophylline, benzodiazepines, etc.). Less potent than famotidine. Gynecomastia with chronic use in humans. Give 30 min before meals.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cimetidine dose range in eastern box turtles, with cited source references: PO, IM 4 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cimetidine in eastern box turtles: PO, IM.
Cimetidine is indicated in eastern box turtles for: gastric and duodenal ulceration; oesophagitis; gastro-oesophageal reflux.
These are general warnings for Cimetidine across species; consult the eastern box turtle dosing table above for species-specific guidance. Inhibits cytochrome P450 enzymes (many drug interactions — theophylline, benzodiazepines, etc.). Less potent than famotidine. Gynecomastia with chronic use in humans. Give 30 min before meals.
Why a species-specific page? Cimetidine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.