Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Cimetidine is dosed at 4 mg/kg PO, IM q8-12h in eastern box turtles, per 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1419 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.11 (Miscellaneous Agents Used in Reptiles). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Cimetidine is used in eastern box turtles for gastric and duodenal ulceration; oesophagitis; gastro-oesophageal reflux. Routes documented in eastern box turtles: PO, IM. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Cimetidine in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tagamet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO, IM | 4 mg/kg | q8-12h | gastric and duodenal ulceration; oesophagitis; gastro-oesophageal reflux | Weak | 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1419 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.11 (Miscellaneous Agents Used in Reptiles). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 4 | IM | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.90 | 4 mg/kg i.m., p.o. q8-12h |
| 4 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.11 | 4 mg/kg PO, IM q8-12h |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitively blocks histamine H2 receptors on parietal cells, reducing basal and stimulated gastric acid secretion.
Inhibits cytochrome P450 enzymes (many drug interactions — theophylline, benzodiazepines, etc.). Less potent than famotidine. Gynecomastia with chronic use in humans. Give 30 min before meals.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cimetidine dose range in eastern box turtles, with cited source references: PO, IM 4 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cimetidine in eastern box turtles: PO, IM.
Cimetidine is indicated in eastern box turtles for: gastric and duodenal ulceration; oesophagitis; gastro-oesophageal reflux.
These are general warnings for Cimetidine across species; consult the eastern box turtle dosing table above for species-specific guidance. Inhibits cytochrome P450 enzymes (many drug interactions — theophylline, benzodiazepines, etc.). Less potent than famotidine. Gynecomastia with chronic use in humans. Give 30 min before meals.
Why a species-specific page? Cimetidine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.