Cat · Felis catus · typical adult weight 2.50–7.00 kg
Cyproheptadine (Respiratory) is dosed at 1–4 mg per cat PO q12h in cats, per Agnew W, Korman R. Pharmacological appetite stimulation: rational choices in the inappetent cat. J Feline Med Surg. 2014;16(9):749-756.; Webb CB. Hepatic lipidosis: Clinical review drawn from collective effort. J Feline Med Surg. 2018;20(3):217-227. doi:10.1177/1098612x18758591 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.356 (2026-08-01).. Cyproheptadine (Respiratory) is used in cats for Feline asthma / appetite stimulation / serotonin syndrome. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Cyproheptadine (Respiratory) in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Periactin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–4 mg per catmax 8 mg total | q12h | Variable; long-term for asthma if effective | Feline asthma / appetite stimulation / serotonin syndrome | Moderate | Agnew W, Korman R. Pharmacological appetite stimulation: rational choices in the inappetent cat. J Feline Med Surg. 2014;16(9):749-756.; Webb CB. Hepatic lipidosis: Clinical review drawn from collective effort. J Feline Med Surg. 2018;20(3):217-227. doi:10.1177/1098612x18758591 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.356 (2026-08-01). |
Need the exact dose for your patient?
Enter your cat's weight to check these cited ranges in the calculator — unit and concentration math done for you.
Piperidine antihistamine with potent 5-HT2A serotonin receptor antagonism and H1 blockade, providing both antiallergic and antiserotonergic effects. Also acts as bronchodilator.
Appetite stimulation is a prominent effect. Sedation possible. Used for feline asthma as bronchodilator adjunct and serotonin syndrome antidote.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cyproheptadine (Respiratory) dose range in cats, with cited source references: PO 1–4 mg per cat q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cyproheptadine (Respiratory) in cats: PO.
Cited course lengths for Cyproheptadine (Respiratory) in cats include: Variable; long-term for asthma if effective. Duration depends on the indication — match it to the specific dose rule in the table above.
Cyproheptadine (Respiratory) is indicated in cats for: Feline asthma / appetite stimulation / serotonin syndrome.
These are general warnings for Cyproheptadine (Respiratory) across species; consult the cat dosing table above for species-specific guidance. Appetite stimulation is a prominent effect. Sedation possible. Used for feline asthma as bronchodilator adjunct and serotonin syndrome antidote.
Why a species-specific page? Cyproheptadine (Respiratory) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.