Cat · Felis catus · typical adult weight 2.50–7.00 kg
Cyproheptadine (Respiratory) is dosed at 1–4 mg per cat PO q12h in cats, per Agnew W, Korman R. Pharmacological appetite stimulation: rational choices in the inappetent cat. J Feline Med Surg. 2014;16(9):749-756.; Webb CB. Hepatic lipidosis: Clinical review drawn from collective effort. J Feline Med Surg. 2018;20(3):217-227. doi:10.1177/1098612x18758591 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.356 (2026-08-01). — Plumb's 10th ed (held) printed p.327, Cyproheptadine monograph spanning p.327-328; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Cyproheptadine (Respiratory) is used in cats for Appetite stimulation. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Cyproheptadine (Respiratory) in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Periactin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–4 mg per catmax 8 mg total | q12h | Variable; long-term for asthma if effective | Appetite stimulation | Moderate | Agnew W, Korman R. Pharmacological appetite stimulation: rational choices in the inappetent cat. J Feline Med Surg. 2014;16(9):749-756.; Webb CB. Hepatic lipidosis: Clinical review drawn from collective effort. J Feline Med Surg. 2018;20(3):217-227. doi:10.1177/1098612x18758591 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.356 (2026-08-01). — Plumb's 10th ed (held) printed p.327, Cyproheptadine monograph spanning p.327-328; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.1–0.5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.120 | 0.1-0.5 mg/kg p.o. q8-12h. Cytarabine (Cytosine arabinoside, Ara-C) (Cytarabine*, Cytosar-U*) POM |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Piperidine antihistamine with potent 5-HT2A serotonin receptor antagonism and H1 blockade, providing both antiallergic and antiserotonergic effects. Also acts as bronchodilator.
Appetite stimulation is a prominent effect. Sedation possible. Used for feline asthma as bronchodilator adjunct and serotonin syndrome antidote.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cyproheptadine (Respiratory) dose range in cats, with cited source references: PO 1–4 mg per cat q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cyproheptadine (Respiratory) in cats: PO.
Cited course lengths for Cyproheptadine (Respiratory) in cats include: Variable; long-term for asthma if effective. Duration depends on the indication — match it to the specific dose rule in the table above.
Cyproheptadine (Respiratory) is indicated in cats for: Appetite stimulation.
These are general warnings for Cyproheptadine (Respiratory) across species; consult the cat dosing table above for species-specific guidance. Appetite stimulation is a prominent effect. Sedation possible. Used for feline asthma as bronchodilator adjunct and serotonin syndrome antidote.
Why a species-specific page? Cyproheptadine (Respiratory) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.