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Dexamethasone for Horse

Equine · Equus caballus · typical adult weight 350.00–700.00 kg

Dexamethasone is used in horse for Inflammation, allergic reactions, recurrent airway obstruction, Inflammatory conditions, recurrent airway obstruction. Routes documented in horse: IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Dexamethasone in horse, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Azium, Dexafort

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV0.02–0.2 mg/kgq24hShort-term onlyInflammation, allergic reactions, recurrent airway obstructionStrongPlumb's Veterinary Drug Handbook, 9th Ed
IV0.02–0.1 mg/kgq24h3-5 days; taper for chronic useInflammatory conditions, recurrent airway obstructionStrongPlumb's Veterinary Drug Handbook

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Mechanism of action

Potent synthetic glucocorticoid. Suppresses inflammation, immune responses, and allergic reactions. 25-30x potency of cortisol.

Side effects & warnings

Immunosuppressive. PU/PD, polyphagia. Avoid in active infections without antibiotic coverage. Prolonged use causes iatrogenic hyperadrenocorticism. Avoid in reptiles if possible (severe immunosuppression).

Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Emergency drugs with horse dosing

Dexamethasone dosing in other species

Why a species-specific page? Dexamethasone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.