Reptile · Centrochelys sulcata · typical adult weight 1.00–40.00 kg
Emodepside-Praziquantel Topical is dosed at 1 ml/kg topical (spot-on) once in sulcata tortoises, per Tang PK, Blake D, Hedley J, et al. Efficacy of a topical formulation containing emodepside and praziquantel (Profender®, Bayer) against nematodes in captive tortoises. J Herp Med Surg. 2017;27:116-122. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.225 (2026-08-01, PENDING REVIEW) doi:10.5818/17-04-107.1. Emodepside-Praziquantel Topical is used in sulcata tortoises for Nematodes (oxyurids). Routes documented in sulcata tortoises: topical (spot-on). A typical adult sulcata tortoise weighs 1.00–40.00 kg. ExoticRx lists 1 cited dose rule for Emodepside-Praziquantel Topical in sulcata tortoises, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Profender
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| topical (spot-on) | 1 ml/kg | once | Nematodes (oxyurids) | Moderate | Tang PK, Blake D, Hedley J, et al. Efficacy of a topical formulation containing emodepside and praziquantel (Profender®, Bayer) against nematodes in captive tortoises. J Herp Med Surg. 2017;27:116-122. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.225 (2026-08-01, PENDING REVIEW) doi:10.5818/17-04-107.1 |
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These ranges are per kg. Enter your sulcata tortoise's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Emodepside acts on latrophilin receptors causing nematode paralysis; praziquantel disrupts cestode tegument. Combination covers roundworms, hookworms, and tapeworms.
Cats only (FDA-approved). Topical application avoids pilling difficulty. Do not apply to broken skin. Oral ingestion during grooming may cause hypersalivation.
Species-specific contraindications and adverse-reaction reports for sulcata tortoises may differ from canine / feline reference data — consult the primary citations listed with each rule.
Emodepside-Praziquantel Topical dose range in sulcata tortoises, with cited source references: topical (spot-on) 1 ml/kg once. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Emodepside-Praziquantel Topical in sulcata tortoises: topical (spot-on).
Emodepside-Praziquantel Topical is indicated in sulcata tortoises for: Nematodes (oxyurids).
These are general warnings for Emodepside-Praziquantel Topical across species; consult the sulcata tortoise dosing table above for species-specific guidance. Cats only (FDA-approved). Topical application avoids pilling difficulty. Do not apply to broken skin. Oral ingestion during grooming may cause hypersalivation.
Why a species-specific page? Emodepside-Praziquantel Topical pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in sulcata tortoises — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.