Reptile · Python regius · typical adult weight 1.00–2.00 kg
Enrofloxacin Injectable is dosed at 5–10 mg/kg IM q48h in ball pythons, per Waxman S, Prados AP, de Lucas JJ, et al. Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after single intramuscular administration in South American rattlesnake (Crotalus durissus terrificus). Pakistan Vet J. 2015;35:494-498.; Waxman S, Prados AP, de Lucas JJ, et al. Pharmacokinetic behavior of enrofloxacin and its metabolite ciprofloxacin in Urutu pit vipers (Bothrops alternatus) after intramuscular administration. J Zoo Wildl Med. 2014;45:78-85. doi:10.1638/2013-0131r.1 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.216 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Enrofloxacin Injectable is used in ball pythons for Respiratory infections. Routes documented in ball pythons: IM. A typical adult ball python weighs 1.00–2.00 kg. ExoticRx lists 1 cited dose rule for Enrofloxacin Injectable in ball pythons, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Baytril Injectable
| Route | Dose | Frequency | Duration | Indication | Evidence |
|---|
| Source |
|---|
| IM | 5–10 mg/kg | q48h | 14-21 days | Respiratory infections | Moderate | Waxman S, Prados AP, de Lucas JJ, et al. Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after single intramuscular administration in South American rattlesnake (Crotalus durissus terrificus). Pakistan Vet J. 2015;35:494-498.; Waxman S, Prados AP, de Lucas JJ, et al. Pharmacokinetic behavior of enrofloxacin and its metabolite ciprofloxacin in Urutu pit vipers (Bothrops alternatus) after intramuscular administration. J Zoo Wildl Med. 2014;45:78-85. doi:10.1638/2013-0131r.1 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.216 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 5–13 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.1 | 5-13 mg/kg PO, IM q24-48h |
| 10 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.1 | 10 mg/kg IM q24h 5 mg/kg IM q24-48h C 5 mg/kg IM q12-24h C |
| 5 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.1 | 10 mg/kg IM q24h 5 mg/kg IM q24-48h C 5 mg/kg IM q12-24h C |
| 5–10 | IM |
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Inhibits bacterial DNA gyrase and topoisomerase IV. Concentration-dependent bactericidal activity. Metabolized to ciprofloxacin.
Do NOT use IV route in small animals (cardiovascular collapse). SC preferred in reptiles. Avoid in young growing animals. Cats: retinal degeneration at >5mg/kg/day.
Species-specific contraindications and adverse-reaction reports for ball pythons may differ from canine / feline reference data — consult the primary citations listed with each rule.
Enrofloxacin Injectable dose range in ball pythons, with cited source references: IM 5–10 mg/kg q48h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Enrofloxacin Injectable in ball pythons: IM.
Cited course lengths for Enrofloxacin Injectable in ball pythons include: 14-21 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Enrofloxacin Injectable is indicated in ball pythons for: Respiratory infections.
These are general warnings for Enrofloxacin Injectable across species; consult the ball python dosing table above for species-specific guidance. Do NOT use IV route in small animals (cardiovascular collapse). SC preferred in reptiles. Avoid in young growing animals. Cats: retinal degeneration at >5mg/kg/day.
Why a species-specific page? Enrofloxacin Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in ball pythons — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 |
| 5-10 mg/kg q24h PO, SC, IM, ICe99 Most species/IM administration is painful and may result in tissue necrosis and sterile abscesses; may cause skin discoloration or tissue necrosis |
| 6.6 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 6.6 mg/kg IM q24h, or 11 mg/kg IM q48h167 Pythons/PD (reticulated pythons); Pseudomonas |
| 11 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 6.6 mg/kg IM q24h, or 11 mg/kg IM q48h167 Pythons/PD (reticulated pythons); Pseudomonas |
| 10 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 10 mg/kg IM q48h338,339,351 Snakes/PK (Burmese pythons, rattlesnakes, pit vipers) |
| 5–10 | ICE | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 5-10 mg/kg PO, SC, IM q24h52 Most species/PK (bullfrogs);52 ICe and topical routes also used but with limited PK data52 |
| 10 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 10 mg/kg topically46 500 mg/L x 6-8 hr batha q24h52 Coqui frogs/detectable tissue concentration for >24 hr, no correlation to plasma concentration |
| Dose (mg/l) | Route | Source | As printed |
|---|---|---|---|
| 500 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 10 mg/kg topically46 500 mg/L x 6-8 hr batha q24h52 Coqui frogs/detectable tissue concentration for >24 hr, no correlation to plasma concentration |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.