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Enrofloxacin for Prairie Dogs

Pocket Pet · Cynomys ludovicianus · typical adult weight 0.70–1.68 kg

Enrofloxacin is dosed at 20 mg/kg SC q 24 h in prairie dogs, per Eshar D, Wright LT, McCullough CE, KuKanich B. Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin following single-dose subcutaneous injection in black-tailed prairie dogs (Cynomys ludovicianus). Am J Vet Res. 2018 Jun;79(6):658-663. doi:10.2460/ajvr.79.6.658. PMID: 30085856. URL: https://pubmed.ncbi.nlm.nih.gov/30085856/. Enrofloxacin is used in prairie dogs for treatment of infections with bacteria for which the minimum inhibitory concentration of enrofloxacin is ≤ 0.5 μg/mL. Routes documented in prairie dogs: SC. A typical adult prairie dog weighs 0.70–1.68 kg. ExoticRx lists 1 cited dose rule for Enrofloxacin in prairie dogs, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Baytril

Dose ranges

RouteDoseFrequencyIndicationEvidenceSource
SC20 mg/kgq 24 htreatment of infections with bacteria for which the minimum inhibitory concentration of enrofloxacin is ≤ 0.5 μg/mLWeakEshar D, Wright LT, McCullough CE, KuKanich B. Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin following single-dose subcutaneous injection in black-tailed prairie dogs (Cynomys ludovicianus). Am J Vet Res. 2018 Jun;79(6):658-663. doi:10.2460/ajvr.79.6.658. PMID: 30085856. URL: https://pubmed.ncbi.nlm.nih.gov/30085856/

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Mechanism of action

Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.

Side effects & warnings

Avoid in growing animals (cartilage damage). Do NOT use in cats at doses >5mg/kg (retinal toxicity). Avoid concurrent use with theophylline.

Species-specific contraindications and adverse-reaction reports for prairie dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.

Frequently asked questions

What is the dose of Enrofloxacin for Prairie Dogs?

Enrofloxacin dose range in prairie dogs, with cited source references: SC 20 mg/kg q 24 h.

How is Enrofloxacin administered in Prairie Dogs?

Documented routes for Enrofloxacin in prairie dogs: SC.

What conditions does Enrofloxacin treat in Prairie Dogs?

Enrofloxacin is indicated in prairie dogs for: treatment of infections with bacteria for which the minimum inhibitory concentration of enrofloxacin is ≤ 0.5 μg/mL.

What are the side effects of Enrofloxacin in Prairie Dogs?

These are general warnings for Enrofloxacin across species; consult the prairie dog dosing table above for species-specific guidance. Avoid in growing animals (cartilage damage). Do NOT use in cats at doses >5mg/kg (retinal toxicity). Avoid concurrent use with theophylline.

Enrofloxacin dosing in other species

Why a species-specific page? Enrofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in prairie dogs — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.