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extended-release buprenorphine for Mouses

Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg

extended-release buprenorphine is dosed at 3.25 mg/kg SC once in mouses, per Navarro KL, et al. Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post-operative hypersensitivity in an incisional pain model in mice (Mus musculus). Animal Models and Experimental Medicine. 2021. DOI 10.1002/ame2.12157; PMID 34179720; PMCID PMC8212827. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC8212827/. extended-release buprenorphine is used in mouses for post-operative analgesia (incisional pain model). Routes documented in mouses: SC. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 2 cited dose rules for extended-release buprenorphine in mouses, drawn from published veterinary references. Verify against current literature before clinical use.

Dose ranges

RouteDoseFrequencyIndicationEvidenceSource
SC3.25 mg/kgoncepost-operative analgesia (incisional pain model)WeakNavarro KL, et al. Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post-operative hypersensitivity in an incisional pain model in mice (Mus musculus). Animal Models and Experimental Medicine. 2021. DOI 10.1002/ame2.12157; PMID 34179720; PMCID PMC8212827. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC8212827/
SC6.5 mg/kgoncepost-operative analgesia (incisional pain model)WeakNavarro KL, et al. Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post-operative hypersensitivity in an incisional pain model in mice (Mus musculus). Animal Models and Experimental Medicine. 2021. DOI 10.1002/ame2.12157; PMID 34179720; PMCID PMC8212827. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC8212827/

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Frequently asked questions

What is the dose of extended-release buprenorphine for Mouses?

extended-release buprenorphine dose ranges in mouses, with cited source references: SC 3.25 mg/kg once; SC 6.5 mg/kg once.

How is extended-release buprenorphine administered in Mouses?

Documented routes for extended-release buprenorphine in mouses: SC.

What conditions does extended-release buprenorphine treat in Mouses?

extended-release buprenorphine is indicated in mouses for: post-operative analgesia (incisional pain model).

Other Uncategorized drugs with mouse dosing

Why a species-specific page? extended-release buprenorphine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mouses — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.