Sustained-release buprenorphine for Mouses
Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg
Sustained-release buprenorphine is dosed at 0.6 mg/kg SC See source in mouses, per Pharmacokinetics and Efficacy of a Long-lasting, Highly Concentrated Buprenorphine Solution in Mice. Journal of the American Association for Laboratory Animal Science (JAALAS), 2021. PMID 32993847; DOI 10.30802/AALAS-JAALAS-20-000049; PMC7831350. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC7831350/. Sustained-release buprenorphine is used in mouses for Analgesia in a surgical model of pain (analgesia for at least 48 h). NOTE: reported by the paper as a finding of 'previous studies' (cited comparator), not a dose administered in this study., post-operative analgesia (incisional pain model). Routes documented in mouses: SC. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 2 cited dose rules for Sustained-release buprenorphine in mouses, drawn from published veterinary references. Verify against current literature before clinical use.
Dose ranges
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 0.6 mg/kg | See source | Analgesia in a surgical model of pain (analgesia for at least 48 h). NOTE: reported by the paper as a finding of 'previous studies' (cited comparator), not a dose administered in this study. | Weak | Pharmacokinetics and Efficacy of a Long-lasting, Highly Concentrated Buprenorphine Solution in Mice. Journal of the American Association for Laboratory Animal Science (JAALAS), 2021. PMID 32993847; DOI 10.30802/AALAS-JAALAS-20-000049; PMC7831350. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC7831350/ |
| SC | 1 mg/kg | once | post-operative analgesia (incisional pain model) | Weak | Navarro KL, et al. Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post-operative hypersensitivity in an incisional pain model in mice (Mus musculus). Animal Models and Experimental Medicine. 2021. DOI 10.1002/ame2.12157; PMID 34179720; PMCID PMC8212827. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC8212827/ |
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These ranges are per kg. Enter your mouse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Frequently asked questions
What is the dose of Sustained-release buprenorphine for Mouses?
Sustained-release buprenorphine dose ranges in mouses, with cited source references: SC 0.6 mg/kg See source; SC 1 mg/kg once.
How is Sustained-release buprenorphine administered in Mouses?
Documented routes for Sustained-release buprenorphine in mouses: SC.
What conditions does Sustained-release buprenorphine treat in Mouses?
Sustained-release buprenorphine is indicated in mouses for: Analgesia in a surgical model of pain (analgesia for at least 48 h). NOTE: reported by the paper as a finding of 'previous studies' (cited comparator), not a dose administered in this study., post-operative analgesia (incisional pain model).
Other Uncategorized drugs with mouse dosing
Why a species-specific page? Sustained-release buprenorphine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mouses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.