What is Sustained-release buprenorphine used for?

Sustained-release buprenorphine is indicated for: Analgesia in a surgical model of pain (analgesia, post-operative analgesia (incisional pain model).

Which species have cited Sustained-release buprenorphine dosing data?

Sustained-release buprenorphine dosing in the ExoticRx formulary covers 1 species: Mouse.

Is Sustained-release buprenorphine a controlled substance?

Sustained-release buprenorphine is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Sustained-release buprenorphine

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Sustained-release buprenorphine is dosed at 0.6 mg/kg SC q72h in mice, per Kendall LV, Wegenast DJ, Smith BJ, et al. Efficacy of sustained-release buprenorphine in an experimental laparotomy model in female mice. J Am Assoc Lab Anim Sci. 2016;55:66-73. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.790 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 9.4 (Analgesic Agents Used in Rodents). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.

Drug Class

Uncategorized

Routes

Indications

Analgesia in a surgical model of pain (analgesia post-operative analgesia (incisional pain model)

Species with Sustained-release buprenorphine dosing data (2 dose rules)

Mouse

Species references:All Mouse drugs

Evidence levels across 2 dose rules

Weak×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

· Kendall LV, Wegenast DJ, Smith BJ, et al. Efficacy of sustained-release buprenorphine in an experimental laparotomy model in female mice. J Am Assoc Lab Anim Sci. 2016;55:66-73. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.790 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 9.4 (Analgesic Agents Used in Rodents). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· Navarro KL, et al. Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post-operative hypersensitivity in an incisional pain model in mice (Mus musculus). Animal Models and Experimental Medicine. 2021. DOI 10.1002/ame2.12157; PMID 34179720; PMCID PMC8212827. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC8212827/

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Calculate Dosage for Sustained-release buprenorphine