Which species have cited Sustained-release buprenorphine dosing data?

Sustained-release buprenorphine dosing in the ExoticRx formulary covers 1 species: Mouse.

Is Sustained-release buprenorphine a controlled substance?

Sustained-release buprenorphine is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Sustained-release buprenorphine

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Sustained-release buprenorphine is dosed at 0.6 mg/kg SC See source in mouses, per Pharmacokinetics and Efficacy of a Long-lasting, Highly Concentrated Buprenorphine Solution in Mice. Journal of the American Association for Laboratory Animal Science (JAALAS), 2021. PMID 32993847; DOI 10.30802/AALAS-JAALAS-20-000049; PMC7831350. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC7831350/. Verify against current literature before clinical use.

Drug Class

Uncategorized

Routes

Indications

Analgesia in a surgical model of pain (analgesianot a dose administered in this study.post-operative analgesia (incisional pain model)

Species with Sustained-release buprenorphine dosing data (2 dose rules)

Mouse

Species references:All Mouse drugs

Evidence levels across 2 dose rules

Weak×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

· Navarro KL, et al. Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post-operative hypersensitivity in an incisional pain model in mice (Mus musculus). Animal Models and Experimental Medicine. 2021. DOI 10.1002/ame2.12157; PMID 34179720; PMCID PMC8212827. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC8212827/
· Pharmacokinetics and Efficacy of a Long-lasting, Highly Concentrated Buprenorphine Solution in Mice. Journal of the American Association for Laboratory Animal Science (JAALAS), 2021. PMID 32993847; DOI 10.30802/AALAS-JAALAS-20-000049; PMC7831350. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC7831350/

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Calculate Dosage for Sustained-release buprenorphine