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Fidaxomicin for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Fidaxomicin is used in cat for Clostridioides difficile colitis. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Fidaxomicin in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Dificid

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO5–10 mg/kgq12h10 daysClostridioides difficile colitisWeakPlumb's Veterinary Drug Handbook, 9th Ed

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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Inhibits bacterial RNA polymerase at a distinct site from rifamycins. Narrow spectrum, primarily active against Clostridioides.

Side effects & warnings

Minimal systemic absorption. GI effects possible. Very limited veterinary data — use extrapolated from human medicine.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with cat dosing

Fidaxomicin dosing in other species

Why a species-specific page? Fidaxomicin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.