Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Hyaluronic Acid (Equine Injectable) is dosed at 20–40 mg per joint INTRA-ARTICULAR weekly for 3 weeks in horses, per FDA-approved label dosages as reproduced in Plumb's: Hyvisc (hyaluronate sodium), Hyalovet, Legend. Plumb's cites no numbered reference on these label rows. Hyaluronic Acid (Equine Injectable) is used in horses for Joint inflammation, osteoarthritis, Synovitis associated with equine osteoarthritis. Routes documented in horses: INTRA-ARTICULAR, IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Hyaluronic Acid (Equine Injectable) in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Legend, Hyalovet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| INTRA-ARTICULAR | 20–40 mg per joint | weekly for 3 weeks | Joint inflammation, osteoarthritis | Strong | FDA-approved label dosages as reproduced in Plumb's: Hyvisc (hyaluronate sodium), Hyalovet, Legend. Plumb's cites no numbered reference on these label rows.Compilation only — we have not located an independent source that prints this figure. |
| IV | 40 mg total | weekly for 3 weeks | Synovitis associated with equine osteoarthritis | Strong | FDA-approved label dosage (Legend, hyaluronate sodium 10 mg/mL, NADA 140-883) as reproduced in Plumb's; NexHA carries the identical 40 mg IV weekly x3 regimen. |
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High molecular weight hyaluronan that restores viscoelastic properties of synovial fluid, inhibits inflammatory mediators, and protects articular cartilage.
IV formulation (Legend) for non-infectious joint dysfunction. Intra-articular injection requires sterile technique. Transient joint effusion may occur with IA injection. Not for use in horses intended for food.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Hyaluronic Acid (Equine Injectable) dose ranges in horses, with cited source references: INTRA-ARTICULAR 20–40 mg per joint weekly for 3 weeks; IV 40 mg total weekly for 3 weeks. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Hyaluronic Acid (Equine Injectable) in horses: INTRA-ARTICULAR, IV.
Hyaluronic Acid (Equine Injectable) is indicated in horses for: Joint inflammation, osteoarthritis, Synovitis associated with equine osteoarthritis.
These are general warnings for Hyaluronic Acid (Equine Injectable) across species; consult the horse dosing table above for species-specific guidance. IV formulation (Legend) for non-infectious joint dysfunction. Intra-articular injection requires sterile technique. Transient joint effusion may occur with IA injection. Not for use in horses intended for food.
Why a species-specific page? Hyaluronic Acid (Equine Injectable) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.