Hyaluronic Acid (Equine Injectable) for Horse
Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Hyaluronic Acid (Equine Injectable) is used in horse for Joint inflammation, osteoarthritis, Synovitis associated with equine osteoarthritis, Non-infectious joint dysfunction. Routes documented in horse: INTRA-ARTICULAR, IV. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 3 cited dose rules for Hyaluronic Acid (Equine Injectable) in horse, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Legend, Hyalovet
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| INTRA-ARTICULAR | 20–40 mg per joint | weekly for 3 weeks | — | Joint inflammation, osteoarthritis | Strong | FDA NADA Label |
| IV | 40 mg total | weekly for 3 weeks | — | Synovitis associated with equine osteoarthritis | Strong | FDA NADA Label |
| IV | 0.008 mg/kg (40mg/horse) | Weekly | 3 weekly treatments | Non-infectious joint dysfunction | Strong | FDA NADA Label |
Absolute dose ceiling, regardless of body weight: 40 mg total (IV).
Need the exact dose for your patient?
These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
High molecular weight hyaluronan that restores viscoelastic properties of synovial fluid, inhibits inflammatory mediators, and protects articular cartilage.
Side effects & warnings
IV formulation (Legend) for non-infectious joint dysfunction. Intra-articular injection requires sterile technique. Transient joint effusion may occur with IA injection. Not for use in horses intended for food.
Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Supplement drugs with horse dosing
Why a species-specific page? Hyaluronic Acid (Equine Injectable) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.