Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Polysulfated Glycosaminoglycan (Equine) is used in horse for Degenerative joint disease. Routes documented in horse: IM. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Polysulfated Glycosaminoglycan (Equine) in horse, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Adequan Equine
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 500 mg total | every 4 days | 7 treatments (28 days) | Degenerative joint disease | Strong | FDA NADA Label |
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Inhibits catabolic enzymes (metalloproteinases, serine proteases) involved in cartilage degradation. Stimulates synovial fluid production and chondrocyte metabolism.
FDA-approved for equine use. Standard protocol: 500mg IM every 4 days for 7 treatments. Not for use in horses intended for food. Mild transient joint effusion may occur.
Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Polysulfated Glycosaminoglycan (Equine) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.