Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Isoxsuprine is dosed at 0.6 mg/kg PO q12h in horses, per Papich, Saunders Handbook of Veterinary Drugs, 4th Ed (2016), printed p.417 (PDF p.445), Large Animal Dosage > Horses — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Isoxsuprine is used in horses for Navicular syndrome, peripheral vasodilation, Navicular disease. Routes documented in horses: PO. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Isoxsuprine in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Vasodilan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.6 mg/kg | q12h | 6-12 weeks | Navicular syndrome, peripheral vasodilation | Weak | Papich, Saunders Handbook of Veterinary Drugs, 4th Ed (2016), printed p.417 (PDF p.445), Large Animal Dosage > Horses — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
| PO | 0.6–1.2 mg/kg | q12h | 6-12 weeks trial; long-term if beneficial | Navicular disease | Weak | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.731 (2026-08-01). — Plumb's 10th ed (held) printed p.703, Isoxsuprine monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.6 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.445 | • Navicular disease and laminitis: 0.6 mg/kg q12h PO for 6-14 weeks. In some |
| 0.6 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.445 | dosing protocols, if 0.6 mg/kg q12h has not improved horse’s condition within |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Peripheral vasodilator with beta-adrenergic stimulant properties. Increases blood flow to extremities including digital circulation in horses.
Used in horses for navicular disease to improve digital blood flow. Efficacy debated in recent literature. May cause tachycardia. Not for use in horses intended for food.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Isoxsuprine dose ranges in horses, with cited source references: PO 0.6 mg/kg q12h; PO 0.6–1.2 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Isoxsuprine in horses: PO.
Cited course lengths for Isoxsuprine in horses include: 6-12 weeks; 6-12 weeks trial; long-term if beneficial. Duration depends on the indication — match it to the specific dose rule in the table above.
Isoxsuprine is indicated in horses for: Navicular syndrome, peripheral vasodilation, Navicular disease.
These are general warnings for Isoxsuprine across species; consult the horse dosing table above for species-specific guidance. Used in horses for navicular disease to improve digital blood flow. Efficacy debated in recent literature. May cause tachycardia. Not for use in horses intended for food.
Why a species-specific page? Isoxsuprine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.