Is Isoxsuprine a controlled substance?

Isoxsuprine is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Isoxsuprine

US brand names:Vasodilan

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Isoxsuprine is dosed at 10 mg/kg PO q12-24h in african grey parrots, per 283. Fitzgerald BC, Dias S, Martorell J. Cardiovascular drugs in avian, small mammal, and reptile medicine. Vet Clin North Am Exot Anim Pract. 2018;21(2):399-442. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.492 doi:10.1016/j.cvex.2018.01.015 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.18 (Miscellaneous Agents Used in Birds). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.

Drug Class

Cardiovascular

Routes

Indications

Clinical signs associatedNavicular diseaseNavicular syndromeperipheral vasodilationPeripheral vasodilation (atherosclerosis, wingtip oedema)See source

Mechanism of Action

Peripheral vasodilator with beta-adrenergic stimulant properties. Increases blood flow to extremities including digital circulation in horses.

Side effects & warnings

Used in horses for navicular disease to improve digital blood flow. Efficacy debated in recent literature. May cause tachycardia. Not for use in horses intended for food.

Species with Isoxsuprine dosing data (8 dose rules)

African Grey Parrot Amazon Parrot Great Horned Owl Harris Hawk Horse (Equine)Peregrine Falcon Red-tailed Hawk

Species references:All African Grey Parrot drugs All Amazon Parrot drugs All Great Horned Owl drugs All Harris Hawk drugs All Horse (Equine) drugs All Peregrine Falcon drugs All Red-tailed Hawk drugs

Evidence levels across 8 dose rules

Moderate×5Weak×3

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 5 published sources

· 283. Fitzgerald BC, Dias S, Martorell J. Cardiovascular drugs in avian, small mammal, and reptile medicine. Vet Clin North Am Exot Anim Pract. 2018;21(2):399-442. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.492 doi:10.1016/j.cvex.2018.01.015 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.18 (Miscellaneous Agents Used in Birds). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· 866. Simone-Freilicher E. Use of isoxsuprine for treatment of clinical signs associated withttpresumptive atherosclerosis in a yellow-naped Amazon parrot (Amazona ochrocephala auropalliata). J Avian Med Surg. 2007;21:215-219. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.492 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.18 (Miscellaneous Agents Used in Birds). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

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