Cat · Felis catus · typical adult weight 2.50–7.00 kg
Leflunomide is dosed at 2–4 mg/kg PO q24h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Leflunomide is used in cats for Immune-mediated disease. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Leflunomide in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Arava
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–4 mg/kg | q24h | Weeks to months | Immune-mediated disease | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits dihydroorotate dehydrogenase blocking de novo pyrimidine synthesis in rapidly dividing lymphocytes. Immunomodulatory.
Used for immune-mediated polyarthritis and other immune-mediated diseases. Hepatotoxic — monitor liver enzymes. Teratogenic. Diarrhea, anorexia. Slow onset (weeks).
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Leflunomide dose range in cats, with cited source references: PO 2–4 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Leflunomide in cats: PO.
Cited course lengths for Leflunomide in cats include: Weeks to months. Duration depends on the indication — match it to the specific dose rule in the table above.
Leflunomide is indicated in cats for: Immune-mediated disease.
These are general warnings for Leflunomide across species; consult the cat dosing table above for species-specific guidance. Used for immune-mediated polyarthritis and other immune-mediated diseases. Hepatotoxic — monitor liver enzymes. Teratogenic. Diarrhea, anorexia. Slow onset (weeks).
Why a species-specific page? Leflunomide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.