Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Methimazole is dosed at 0.5–2 mg/kg PO q24h in guinea pigs, per Mayer J, Wagner R, Taeymans O. Advanced diagnostic approaches and current management of thyroid pathologies in guinea pigs. Vet Clin North Am Exot Anim Pract. 2010;13:509-523. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.801 (2026-08-01, PENDING REVIEW) doi:10.1016/j.cvex.2010.05.009. Methimazole is used in guinea pigs for Hyperthyroidism. Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Methimazole in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tapazole, Felimazole
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q24h | Hyperthyroidism | Moderate | Mayer J, Wagner R, Taeymans O. Advanced diagnostic approaches and current management of thyroid pathologies in guinea pigs. Vet Clin North Am Exot Anim Pract. 2010;13:509-523. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.801 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits thyroid peroxidase, blocking iodine organification and thyroid hormone synthesis. Does not destroy thyroid tissue.
Cats: monitor renal function (treating hyperthyroidism may unmask underlying renal disease). Side effects include anorexia, vomiting, facial pruritus, and blood dyscrasias. Monitor CBC and liver enzymes.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Methimazole dose range in guinea pigs, with cited source references: PO 0.5–2 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Methimazole in guinea pigs: PO.
Methimazole is indicated in guinea pigs for: Hyperthyroidism.
These are general warnings for Methimazole across species; consult the guinea pig dosing table above for species-specific guidance. Cats: monitor renal function (treating hyperthyroidism may unmask underlying renal disease). Side effects include anorexia, vomiting, facial pruritus, and blood dyscrasias. Monitor CBC and liver enzymes.
Why a species-specific page? Methimazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.