Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Metronidazole is dosed at 25 mg/kg PO q24h in eastern box turtles, per 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1406 (2026-08-01, PENDING REVIEW). Metronidazole is used in eastern box turtles for amoebiasis, anaerobic bacterial infection. Routes documented in eastern box turtles: PO. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 2 cited dose rules for Metronidazole in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Flagyl
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 25 mg/kg | q24h | amoebiasis | Weak | 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1406 (2026-08-01, PENDING REVIEW) |
| PO | 20 mg/kg | q48h | anaerobic bacterial infection | Weak | 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1403 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Disrupts DNA structure in anaerobic organisms via reduction of nitro group, forming cytotoxic intermediates.
Neurotoxicity at high doses or prolonged use (ataxia, seizures). Avoid in pregnant animals. Hepatotoxic at high doses.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Metronidazole dose ranges in eastern box turtles, with cited source references: PO 25 mg/kg q24h; PO 20 mg/kg q48h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Metronidazole in eastern box turtles: PO.
Metronidazole is indicated in eastern box turtles for: amoebiasis, anaerobic bacterial infection.
These are general warnings for Metronidazole across species; consult the eastern box turtle dosing table above for species-specific guidance. Neurotoxicity at high doses or prolonged use (ataxia, seizures). Avoid in pregnant animals. Hepatotoxic at high doses.
Why a species-specific page? Metronidazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.