Reptile · Pantherophis guttatus · typical adult weight 0.20–0.90 kg
Metronidazole is dosed at 20 mg/kg PO q48h x >=7 days in corn snakes, per Funk RS, Diethelm G. Reptile formulary. In: Mader DR, eds. Reptile Medicine and Surgey, 2nd ed., Saunders/Elsevier, St. Louis, MO; 2006:1119-1139. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.218 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Metronidazole is used in corn snakes for Anaerobic bacterial infection. Routes documented in corn snakes: PO. A typical adult corn snake weighs 0.20–0.90 kg. ExoticRx lists 1 cited dose rule for Metronidazole in corn snakes, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Flagyl
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 20 mg/kg | q48h x >=7 days | Anaerobic bacterial infection | Weak | Funk RS, Diethelm G. Reptile formulary. In: Mader DR, eds. Reptile Medicine and Surgey, 2nd ed., Saunders/Elsevier, St. Louis, MO; 2006:1119-1139. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.218 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 20 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.4 | 50 mg/kg PO q48h43a 20 mg/kg PO q24- Ig 48h Ch 40-60 mg/kg PO Ge q7d x2-3 doses 40-200 mg/kg PO, repeat in 14 days |
| 50 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.4 | 50 mg/kg PO q48h43a 20 mg/kg PO q24- Ig 48h Ch 40-60 mg/kg PO Ge q7d x2-3 doses 40-200 mg/kg PO, repeat in 14 days |
| 40–60 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.4 | 50 mg/kg PO q48h43a 20 mg/kg PO q24- Ig 48h Ch 40-60 mg/kg PO Ge q7d x2-3 doses 40-200 mg/kg PO, repeat in 14 days |
Need the exact dose for your patient?
These ranges are per kg. Enter your corn snake's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Disrupts DNA structure in anaerobic organisms via reduction of nitro group, forming cytotoxic intermediates.
Neurotoxicity at high doses or prolonged use (ataxia, seizures). Avoid in pregnant animals. Hepatotoxic at high doses.
Species-specific contraindications and adverse-reaction reports for corn snakes may differ from canine / feline reference data — consult the primary citations listed with each rule.
Metronidazole dose range in corn snakes, with cited source references: PO 20 mg/kg q48h x >=7 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Metronidazole in corn snakes: PO.
Metronidazole is indicated in corn snakes for: Anaerobic bacterial infection.
These are general warnings for Metronidazole across species; consult the corn snake dosing table above for species-specific guidance. Neurotoxicity at high doses or prolonged use (ataxia, seizures). Avoid in pregnant animals. Hepatotoxic at high doses.
Why a species-specific page? Metronidazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in corn snakes — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 40–200 |
| PO |
| Carpenter's Exotic Animal Formulary, 6th edTable 4.4 |
| 50 mg/kg PO q48h43a 20 mg/kg PO q24- Ig 48h Ch 40-60 mg/kg PO Ge q7d x2-3 doses 40-200 mg/kg PO, repeat in 14 days |
| 20 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 20 mg/kg PO q48h31 Corn snakes/PK; 28°C (82°F); protozoa |
| 50 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 50 mg/kg PO q24h × 7-14 days167 Most species/may be administered concurrently with amikacin for broader spectrum; because of potential side effects at this dose, a lower dose may b |
| 40–100 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 40-100 mg/kg PO, repeat in 10-14 days88 Most species/flagellate overgrowth |
| 40 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 40 mg/kg PO, repeat in 14 days90,143 Uracoan rattler, milk, tricolor king, and indigo snakes/flagellates |
| 12.5–50 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.8 | 12.5-50 mg/kg PO88 Most species/appetite stimulant (anecdotal; presumably associated with antiprotozoal activity) |
| 10 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 10 mg/kg PO q24h × 5-10 days52 Protozoa; for unfamiliar or sensitive species |
| 10 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 10 mg/kg IV q24h × 2 days52 Anaerobic infections |
| 12 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 12 mg/kg topically q24h × 5-10 days52 For chronic diarrhea |
| 60 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 60 mg/kg topically q24h × 3 days52 Anaerobic infections |
| 100 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 100 mg/kg PO q3d52 Protozoa |
| 100–150 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 100-150 mg/kg PO, repeat in 2-3 wk or prn52 Protozoa (i.e., Entamoeba, Hexamita, Opalina) |
| Dose (mg/l) | Route | Source | As printed |
|---|---|---|---|
| 50 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 50 mg/L × 24 hr bath52 500 mg/100 g feed × 3-4 treatments52 Aquatic amphibians/protozoa Ciliates |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.