Reptile · Pantherophis guttatus · typical adult weight 0.20–0.90 kg
Paromomycin is dosed at 100 mg/kg PO once daily for 10 days, then twice weekly for 90 in corn snakes, per Shimizu U, Kurihara M, Tamukai K, Yamada K. Treatment of esophagogastric intussusception due to cryptosporidiosis using paromomycin in a corn snake (Pantherophis guttatus). J Vet Med Sci. 2025;87(4):389-393. doi:10.1292/jvms.24-0483 https://europepmc.org/article/MED/39924250. Paromomycin is used in corn snakes for Cryptosporidiosis (gastric), here with secondary esophagogastric intussusception. Routes documented in corn snakes: PO. A typical adult corn snake weighs 0.20–0.90 kg. ExoticRx lists 1 cited dose rule for Paromomycin in corn snakes, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Humatin
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 100 mg/kg | once daily for 10 days, then twice weekly for 90 | Cryptosporidiosis (gastric), here with secondary esophagogastric intussusception | Anecdotal | Shimizu U, Kurihara M, Tamukai K, Yamada K. Treatment of esophagogastric intussusception due to cryptosporidiosis using paromomycin in a corn snake (Pantherophis guttatus). J Vet Med Sci. 2025;87(4):389-393. doi:10.1292/jvms.24-0483 https://europepmc.org/article/MED/39924250 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 100 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.4 | 100 mg/kg PO q24h x 7 days, then 2x/wk x 3 mo |
| 360 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.4 | 360 mg/kg PO 2x/wk ×6 wk |
| 360 | IN | Carpenter's Exotic Animal Formulary, 6th edTable 4.4 | 360 mg/kg 2x/wk x 6 wk in food44a |
| 35–100 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed |
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These ranges are per kg. Enter your corn snake's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Aminoglycoside that binds 30S ribosomal subunit. Poorly absorbed orally — acts locally in the GI tract against protozoa and bacteria.
Minimal systemic absorption. Used for GI protozoal infections (Giardia, Cryptosporidium). Ototoxicity/nephrotoxicity if absorbed systemically.
Species-specific contraindications and adverse-reaction reports for corn snakes may differ from canine / feline reference data — consult the primary citations listed with each rule.
Paromomycin dose range in corn snakes, with cited source references: PO 100 mg/kg once daily for 10 days, then twice weekly for 90. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Paromomycin in corn snakes: PO.
Paromomycin is indicated in corn snakes for: Cryptosporidiosis (gastric), here with secondary esophagogastric intussusception.
These are general warnings for Paromomycin across species; consult the corn snake dosing table above for species-specific guidance. Minimal systemic absorption. Used for GI protozoal infections (Giardia, Cryptosporidium). Ototoxicity/nephrotoxicity if absorbed systemically.
Why a species-specific page? Paromomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in corn snakes — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 35-100 mg/kg PO q24h × ≤ 28 days88,143 Most species/amoebae |
| 100 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 100 mg/kg PO q24h × 7 days, then 2×/wk × 3 mo59 Snakes/cryptosporidia; reduced clinical signs and oocyte shedding; does not eliminate the organism |
| 50–75 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 50-75 mg/kg PO q24h52 Gastrointestinal protozoa |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.