ExoticRx · exoticrx.com/drugs/paromomycin
US brand names:Humatin
Paromomycin is dosed at 100 mg/kg PO q24h × 7 days, then 2x/wk × 3 mo in ball pythons, per Cranfield MR, Graczyk TK. Cryptosoporidiosis. In: Mader DR, eds. Reptile Medicine and Surgery, 2nd ed., Saunders/Elsevier, St. Louis, MO; 2006:756-762. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.229 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.4 (Antiparasitic Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Verify against current literature before clinical use.
Aminoglycoside that binds 30S ribosomal subunit. Poorly absorbed orally — acts locally in the GI tract against protozoa and bacteria.
Minimal systemic absorption. Used for GI protozoal infections (Giardia, Cryptosporidium). Ototoxicity/nephrotoxicity if absorbed systemically.
Species references:All African Grey Parrot drugsAll Ball Python drugsAll Cat (Domestic) drugsAll Corn Snake drugsAll Dog (Domestic) drugsAll Ferret drugsAll Leopard Gecko drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 7 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 25–35 mg/kg | q12h | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.986, Paromomycin monograph spanning p.986-987; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.987, Paromomycin monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Cat (Domestic) | PO | 125–165 mg/kg | q12h | Weak | Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), p.610 (PDF 638), Small Animal Dosage — Cats — LOCATOR CONVENTION 2026-08-07: 'p.610' is the PRINTED page number, confirmed by finding the drug named on it in the held copy. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.