ExoticRx · exoticrx.com/drugs/monepantel
US brand names:Zolvix
Monepantel is dosed at 2.5 mg/kg PO Single dose in dogs, per Papich Handbook of Veterinary Drugs, 5th Ed. Verify against current literature before clinical use.
Agonist of nematode-specific acetylcholine receptor (MPHCO-1), causing spastic paralysis. No cross-resistance with existing anthelmintic classes.
Primarily for ruminants but investigational in companion animals. Novel resistance class. Do not use in food-producing animals in some jurisdictions.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Goat (Caprine) drugsAll Sheep (Ovine) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 4 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2.5 mg/kg | Single dose | Extrapolated | Papich Handbook of Veterinary Drugs, 5th Ed |
| Cat (Domestic) | PO | 2.5 mg/kg | Single dose | Extrapolated | Papich Handbook of Veterinary Drugs, 5th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.