ExoticRx · exoticrx.com/drugs/niacinamide
US brand names:Nicotinamide
Inhibits phosphodiesterase, reducing inflammatory mediator release from mast cells and neutrophils. Blocks antigen-induced lymphocyte transformation.
GI upset possible. Often combined with tetracycline/doxycycline for immune-mediated skin diseases (pemphigus, discoid lupus). Generally well-tolerated.
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