Cat · Felis catus · typical adult weight 2.50–7.00 kg
Nitrofurantoin is used in cat for Lower UTI (cystitis). Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Nitrofurantoin in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Macrodantin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 4.4–5 mg/kg | q8h | 7-14 days | Lower UTI (cystitis) | Weak | Papich Handbook of Veterinary Drugs, 5th Ed |
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Reduced by bacterial enzymes to reactive intermediates that damage DNA, ribosomes, and other macromolecules. Concentrated in urine.
Only effective for lower urinary tract infections (requires urinary concentration). GI upset common. Avoid in renal failure (inadequate urinary concentration). Pulmonary toxicity rare.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Nitrofurantoin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.