Reptile · Eublepharis macularius · typical adult weight 0.04–0.10 kg
Prednisolone is dosed at 0.5 mg/kg PO, SC, IM q24h x 14 days, then q48h until PCV stable in leopard geckos, per 243. Klaphake E, Gibbons PM, Sladky KK, et al. Reptiles. In: Carpenter JW, eds. Exotic Animal Formulary, 5th ed., Elsevier, St. Louis, MO; 2018:81-166. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.261 (2026-08-01, PENDING REVIEW). Prednisolone is used in leopard geckos for Autoimmune haemolytic anaemia. Routes documented in leopard geckos: PO, SC, IM. A typical adult leopard gecko weighs 0.04–0.10 kg. ExoticRx lists 1 cited dose rule for Prednisolone in leopard geckos, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Delta-Cortef, Prelone
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO, SC, IM | 0.5 mg/kg | q24h x 14 days, then q48h until PCV stable | Autoimmune haemolytic anaemia | Weak | 243. Klaphake E, Gibbons PM, Sladky KK, et al. Reptiles. In: Carpenter JW, eds. Exotic Animal Formulary, 5th ed., Elsevier, St. Louis, MO; 2018:81-166. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.261 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your leopard gecko's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds intracellular glucocorticoid receptors, modulating gene transcription. Suppresses inflammatory and immune responses at multiple levels.
PU/PD, polyphagia, weight gain, iatrogenic Cushing's. Immunosuppression risk. GI ulceration (especially with NSAIDs). Do not abruptly discontinue after chronic use. Cats require prednisolone (not prednisone).
Species-specific contraindications and adverse-reaction reports for leopard geckos may differ from canine / feline reference data — consult the primary citations listed with each rule.
Prednisolone dose range in leopard geckos, with cited source references: PO, SC, IM 0.5 mg/kg q24h x 14 days, then q48h until PCV stable. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Prednisolone in leopard geckos: PO, SC, IM.
Prednisolone is indicated in leopard geckos for: Autoimmune haemolytic anaemia.
These are general warnings for Prednisolone across species; consult the leopard gecko dosing table above for species-specific guidance. PU/PD, polyphagia, weight gain, iatrogenic Cushing's. Immunosuppression risk. GI ulceration (especially with NSAIDs). Do not abruptly discontinue after chronic use. Cats require prednisolone (not prednisone).
Why a species-specific page? Prednisolone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in leopard geckos — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.