Quinupristin-Dalfopristin for Cat
Cat · Felis catus · typical adult weight 2.50–7.00 kg
Quinupristin-Dalfopristin is used in cat for Resistant gram-positive infections. Routes documented in cat: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Quinupristin-Dalfopristin in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Synercid
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 7.5 mg/kg | q8-12h | 7-14 days | Resistant gram-positive infections | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Streptogramin A (dalfopristin) and B (quinupristin) bind sequentially to 50S subunit creating a stable drug-ribosome complex. Synergistically bactericidal.
Side effects & warnings
Arthralgia/myalgia common. Infusion site reactions. Hepatic CYP3A4 inhibitor. Must use central line. Very limited veterinary data.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antibiotic drugs with cat dosing
Quinupristin-Dalfopristin dosing in other species
Why a species-specific page? Quinupristin-Dalfopristin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.