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Tramadol for Guinea Pig

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

Tramadol is used in guinea pig for Pain management. Routes documented in guinea pig: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Tramadol in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO5–10 mg/kgq12hAs neededPain managementExtrapolatedCarpenter's Exotic Animal Formulary, 6th Ed

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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Weak mu-opioid receptor agonist plus norepinephrine and serotonin reuptake inhibition. Dual mechanism of analgesia.

Side effects & warnings

Dogs metabolize to O-desmethyltramadol poorly compared to humans (reduced opioid effect). May cause sedation, dysphoria. Serotonin syndrome risk with concurrent SSRIs. Cats may respond better than dogs.

Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Analgesic drugs with guinea pig dosing

Tramadol dosing in other species

Why a species-specific page? Tramadol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.