ExoticRx · exoticrx.com/drugs/tretinoin-topical
US brand names:Retin-A, Tretin-X
All-trans retinoic acid that binds nuclear retinoic acid receptors (RARs), modulating gene transcription for cell differentiation, proliferation, and keratinization.
Skin irritation and photosensitivity common. Start with lowest concentration. Teratogenic — avoid in breeding animals. Limited veterinary use for comedones and keratinization disorders.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Topical | Apply to affected areas only | Apply to dorsum q24-48h | Moderate | Miller WH, Small Animal Dermatology, 7th Ed |
| Dog (Domestic) | Topical | Start with lowest concentration (0.025%) | Apply thin layer q24h-q48h to affected area | Weak | Miller WH, Small Animal Dermatology, 7th Ed |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.