Amphibian · Xenopus laevis · typical adult weight 0.05–0.25 kg
Tricaine Methanesulfonate is dosed at 2 g/L bath water Immersion (bath) single immersion to effect, per anaesthetic in african clawed frogs, per Smith BD, Vail KJ, Carroll GL, Taylor MC, Jeffery ND, Vemulapalli TH, et al. Comparison of Etomidate, Benzocaine, and MS222 Anesthesia with and without Subsequent Flunixin Meglumine Analgesia in African Clawed Frogs (Xenopus laevis). J Am Assoc Lab Anim Sci. 2018;57(2):202-209. Tricaine Methanesulfonate is used in african clawed frogs for General anaesthesia for surgery. Routes documented in african clawed frogs: Immersion (bath). A typical adult african clawed frog weighs 0.05–0.25 kg. ExoticRx lists 1 cited dose rule for Tricaine Methanesulfonate in african clawed frogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: MS-222, Finquel
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Immersion (bath) | 2 g/L bath water | single immersion to effect, per anaesthetic | Contact time = submerge until a surgical plane is reached; mean induction 3.6 +/- 1.6 min (95% CI 2.9-4.4), mean recovery 15.8 +/- 16.8 min (95% CI 9.5-24). Bath prepared by dissolving MS-222 in the animal's own recirculating-system tank water and titrating with sodium bicarbonate to pH 7.0. | General anaesthesia for surgery |
| Smith BD, Vail KJ, Carroll GL, Taylor MC, Jeffery ND, Vemulapalli TH, et al. Comparison of Etomidate, Benzocaine, and MS222 Anesthesia with and without Subsequent Flunixin Meglumine Analgesia in African Clawed Frogs (Xenopus laevis). J Am Assoc Lab Anim Sci. 2018;57(2):202-209. https://pmc.ncbi.nlm.nih.gov/articles/PMC5868386/Compilation only — we have not located an independent source that prints this figure. |
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Enter your african clawed frog's weight to check these cited ranges in the calculator — unit and concentration math done for you.
Sodium channel blocker absorbed through gills and skin. Provides sedation, anesthesia, and immobilization in aquatic species via neural blockade.
Aquatic species (fish, amphibians). Buffer solution to neutral pH (acidic otherwise). 21-day withdrawal for food fish. Wear gloves (skin irritant). Monitor opercular movement.
Species-specific contraindications and adverse-reaction reports for african clawed frogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tricaine Methanesulfonate dose range in african clawed frogs, with cited source references: Immersion (bath) 2 g/L bath water single immersion to effect, per anaesthetic. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tricaine Methanesulfonate in african clawed frogs: Immersion (bath).
Cited course lengths for Tricaine Methanesulfonate in african clawed frogs include: Contact time = submerge until a surgical plane is reached; mean induction 3.6 +/- 1.6 min (95% CI 2.9-4.4), mean recovery 15.8 +/- 16.8 min (95% CI 9.5-24). Bath prepared by dissolving MS-222 in the animal's own recirculating-system tank water and titrating with sodium bicarbonate to pH 7.0.. Duration depends on the indication — match it to the specific dose rule in the table above.
Tricaine Methanesulfonate is indicated in african clawed frogs for: General anaesthesia for surgery.
These are general warnings for Tricaine Methanesulfonate across species; consult the african clawed frog dosing table above for species-specific guidance. Aquatic species (fish, amphibians). Buffer solution to neutral pH (acidic otherwise). 21-day withdrawal for food fish. Wear gloves (skin irritant). Monitor opercular movement.
Why a species-specific page? Tricaine Methanesulfonate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in african clawed frogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.