Fish · Carassius auratus · typical adult weight 0.01–3.00 kg
Tricaine Methanesulfonate is dosed at 37 mg/L water (transport sedation) Immersion (bath) continuous immersion during transport in goldfish, per SYNCAINE (tricaine methanesulfonate) powder for solution, package insert. Western Chemical Inc./Syndel. Approved by FDA under ANADA #200-226. Tricaine Methanesulfonate is used in goldfish for Sedation for transport, induction of anaesthesia, maintenance of anaesthesia. Routes documented in goldfish: Immersion (bath), by immersion, immersion. A typical adult goldfish weighs 0.01–3.00 kg. ExoticRx lists 3 cited dose rules for Tricaine Methanesulfonate in goldfish, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: MS-222, Finquel
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Immersion (bath) | 37 mg/L water (transport sedation) | continuous immersion during transport | Contact time as printed: induction within 15 minutes, and maintenance of sedation for up to 48 hours at 24-27 C (75-81 F). The label ties the 48-hour figure to fish transport. | Sedation for transport | Moderate |
| SYNCAINE (tricaine methanesulfonate) powder for solution, package insert. Western Chemical Inc./Syndel. Approved by FDA under ANADA #200-226. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=73bd7576-ce0d-4d70-a625-7c492ffdbe0a |
| by immersion | 50–250 mg/l | not stated in the cited source | — | induction of anaesthesia | Moderate | Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.303.Compilation only — we have not located an independent source that prints this figure. |
| immersion | 25–100 mg/l | not stated in the cited source | NONE IS PRINTED. The monograph states instead: 'The stage of anaesthesia reached is determined by the concentration used and the duration of exposure, since absorption continues throughout the period of immersion.' Exposure is therefore titrated to depth of anaesthesia and monitored, not timed. The only printed time figures belong elsewhere: the 12-24 h pre-anaesthetic food withhold, and the >=60 min post-respiratory-arrest hold that is part of the EUTHANASIA regimen. | maintenance of anaesthesia | Moderate | Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.303.Compilation only — we have not located an independent source that prints this figure. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/l) | Route | Source | As printed |
|---|---|---|---|
| 15–50 | IMMERSION | Carpenter's Exotic Animal Formulary, 6th edTable 2.3 | 15-50 mg/L bath |
| 50–100 | IMMERSION | Carpenter's Exotic Animal Formulary, 6th edTable 2.3 | 50-100 mg/L bath Ane induction; 50- 60 mg/L maintenance |
| 50–60 | IMMERSION | Carpenter's Exotic Animal Formulary, 6th edTable 2.3 | 50-100 mg/L bath Ane induction; 50- 60 mg/L maintenance |
| 100 | IMMERSION | Carpenter's Exotic Animal Formulary, 6th edTable 2.3 | 100 mg/L and 200 mg/L bath 1 g/L water spray |
| 100–200 |
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Sodium channel blocker absorbed through gills and skin. Provides sedation, anesthesia, and immobilization in aquatic species via neural blockade.
Aquatic species (fish, amphibians). Buffer solution to neutral pH (acidic otherwise). 21-day withdrawal for food fish. Wear gloves (skin irritant). Monitor opercular movement.
Species-specific contraindications and adverse-reaction reports for goldfish may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tricaine Methanesulfonate dose ranges in goldfish, with cited source references: Immersion (bath) 37 mg/L water (transport sedation) continuous immersion during transport; by immersion 50–250 mg/l not stated in the cited source; immersion 25–100 mg/l not stated in the cited source. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tricaine Methanesulfonate in goldfish: Immersion (bath), by immersion, immersion.
Cited course lengths for Tricaine Methanesulfonate in goldfish include: Contact time as printed: induction within 15 minutes, and maintenance of sedation for up to 48 hours at 24-27 C (75-81 F). The label ties the 48-hour figure to fish transport.; NONE IS PRINTED. The monograph states instead: 'The stage of anaesthesia reached is determined by the concentration used and the duration of exposure, since absorption continues throughout the period of immersion.' Exposure is therefore titrated to depth of anaesthesia and monitored, not timed. The only printed time figures belong elsewhere: the 12-24 h pre-anaesthetic food withhold, and the >=60 min post-respiratory-arrest hold that is part of the EUTHANASIA regimen.. Duration depends on the indication — match it to the specific dose rule in the table above.
Tricaine Methanesulfonate is indicated in goldfish for: Sedation for transport, induction of anaesthesia, maintenance of anaesthesia.
These are general warnings for Tricaine Methanesulfonate across species; consult the goldfish dosing table above for species-specific guidance. Aquatic species (fish, amphibians). Buffer solution to neutral pH (acidic otherwise). 21-day withdrawal for food fish. Wear gloves (skin irritant). Monitor opercular movement.
Why a species-specific page? Tricaine Methanesulfonate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in goldfish — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| IMMERSION |
| Carpenter's Exotic Animal Formulary, 6th edTable 2.3 |
| 100-200 mg/L bath induction; 50- 100 mg/L maintenance |
| 200 | IMMERSION | Carpenter's Exotic Animal Formulary, 6th edTable 2.3 | 100 mg/L and 200 mg/L bath 1 g/L water spray |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.