Trimethoprim-Sulfamethoxazole for Russian Tortoises
Reptile · Testudo horsfieldii · typical adult weight 0.23–0.91 kg
Trimethoprim-Sulfamethoxazole is dosed at 30 mg/kg PO q 24 h in russian tortoises, per Merck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles. Trimethoprim-Sulfamethoxazole (Antibiotic) has cited veterinary dosing for russian tortoises. Routes documented in russian tortoises: PO. A typical adult russian tortoise weighs 0.23–0.91 kg. ExoticRx lists 1 cited dose rule for Trimethoprim-Sulfamethoxazole in russian tortoises, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Bactrim, TMS
Dose ranges
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 30 mg/kg | q 24 h | — | Weak | Merck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles |
Need the exact dose for your patient?
These ranges are per kg. Enter your russian tortoise's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Sequential blockade of folate synthesis: sulfamethoxazole inhibits dihydropteroate synthase; trimethoprim inhibits dihydrofolate reductase.
Side effects & warnings
May cause keratoconjunctivitis sicca (KCS) in dogs with prolonged use. Can cause bone marrow suppression. Avoid in animals with hepatic disease. Adequate hydration required.
Species-specific contraindications and adverse-reaction reports for russian tortoises may differ from canine / feline reference data — consult the primary citations listed with each rule.
Frequently asked questions
What is the dose of Trimethoprim-Sulfamethoxazole for Russian Tortoises?
Trimethoprim-Sulfamethoxazole dose range in russian tortoises, with cited source references: PO 30 mg/kg q 24 h.
How is Trimethoprim-Sulfamethoxazole administered in Russian Tortoises?
Documented routes for Trimethoprim-Sulfamethoxazole in russian tortoises: PO.
What are the side effects of Trimethoprim-Sulfamethoxazole in Russian Tortoises?
These are general warnings for Trimethoprim-Sulfamethoxazole across species; consult the russian tortoise dosing table above for species-specific guidance. May cause keratoconjunctivitis sicca (KCS) in dogs with prolonged use. Can cause bone marrow suppression. Avoid in animals with hepatic disease. Adequate hydration required.
Other Antibiotic drugs with russian tortoise dosing
Trimethoprim-Sulfamethoxazole dosing in other species
Why a species-specific page? Trimethoprim-Sulfamethoxazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in russian tortoises — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.