Bird · Amazona spp. · typical adult weight 0.35–0.55 kg
Zonisamide is dosed at 20 mg/kg PO q12h in amazon parrots, per 472. Keller KA, Guzman DS.M, Boothe DM, et al. Pharmacokinetics and safety of zonisamide after oral administration of single and multiple doses to Hispaniolan amazon parrots (Amazona ventralis). Am J Vet Res. 2019;80(2):195-200. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.474 (2026-08-01, PENDING REVIEW). Zonisamide is used in amazon parrots for Seizure management; PK-derived. Routes documented in amazon parrots: PO. A typical adult amazon parrot weighs 0.35–0.55 kg. ExoticRx lists 1 cited dose rule for Zonisamide in amazon parrots, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zonegran
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 20 mg/kg | q12h | Seizure management; PK-derived | Moderate | 472. Keller KA, Guzman DS.M, Boothe DM, et al. Pharmacokinetics and safety of zonisamide after oral administration of single and multiple doses to Hispaniolan amazon parrots (Amazona ventralis). Am J Vet Res. 2019;80(2):195-200. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.474 (2026-08-01, PENDING REVIEW) |
Need the exact dose for your patient?
These ranges are per kg. Enter your amazon parrot's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Multiple mechanisms: blocks voltage-gated sodium and T-type calcium channels, enhances GABA release, and has mild carbonic anhydrase inhibitory activity.
Second-line anticonvulsant or add-on therapy. Sedation, ataxia, GI upset. Decreased appetite in some dogs. Renal tubular acidosis reported (rare). Monitor serum levels. Dogs and cats.
Species-specific contraindications and adverse-reaction reports for amazon parrots may differ from canine / feline reference data — consult the primary citations listed with each rule.
Zonisamide dose range in amazon parrots, with cited source references: PO 20 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Zonisamide in amazon parrots: PO.
Zonisamide is indicated in amazon parrots for: Seizure management; PK-derived.
These are general warnings for Zonisamide across species; consult the amazon parrot dosing table above for species-specific guidance. Second-line anticonvulsant or add-on therapy. Sedation, ataxia, GI upset. Decreased appetite in some dogs. Renal tubular acidosis reported (rare). Monitor serum levels. Dogs and cats.
Why a species-specific page? Zonisamide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in amazon parrots — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.