Anaphylaxis in Guinea Pigs
Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
2 cited drugs treat Anaphylaxis in guinea pigs: Diphenhydramine, Ephedrine.
Acute systemic IgE-mediated hypersensitivity. Adrenaline (epinephrine) is the universal first-line; antihistamines and corticosteroids play adjunct roles. Prepare for biphasic reactions over 24 hours.
The overview above describes Anaphylaxis across species; the citations below are the ExoticRx dose rules scoped to guinea pigs — a reference list, not new species-specific clinical guidance.
Diphenhydramine(Benadryl)
Antihistamine| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 1–5 mg/kg | prn | Antihistamine; anaphylaxis | Moderate | Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. / Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.796 (2026-08-01, PENDING REVIEW) |
Ephedrine
Respiratory| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO, IV | 1 mg/kg | prn | Antihistamine; anaphylaxis / stimulant | Weak | Laird KL, Swindle MM, Flecknell PA. Handbook of Rodent and Rabbit Medicine, Pergamon, New York, NY; 1996. / Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.800 (2026-08-01, PENDING REVIEW) |
Other conditions in Guinea Pigs
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.