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Respiratory Infections in Guinea Pigs

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

4 cited drugs treat Respiratory Infections in guinea pigs: Azithromycin, Doxycycline, Enrofloxacin, Trimethoprim-Sulfamethoxazole.

Upper- and lower-respiratory bacterial, mycoplasmal, and fungal infection. Includes bovine respiratory disease complex (BRD) in cattle, pneumonia in companion species, and air sacculitis in birds. Antimicrobial choice often requires species-specific evidence.

The overview above describes Respiratory Infections across species; the citations below are the ExoticRx dose rules scoped to guinea pigs — a reference list, not new species-specific clinical guidance.

Azithromycin(Zithromax)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO15–30 mg/kgq24h7-14 daysRespiratory infectionsWeakFehr M, Sassenburg L, Zwart P. Krankheiten der Heimtiere, 8th ed., Schluetersche Verlagsgesellschaft, Hannover, Germany; 2015. / 130. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).Compilation only — we have not located an independent source that prints this figure.

Doxycycline(Vibramycin)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO2.5–5 mg/kgq12h10-14 daysRespiratory infectionsModerateMorrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).Compilation only — we have not located an independent source that prints this figure.
PO2.5–5 mg/kgq12h14-21 daysPneumonia (may be combined with enrofloxacin)ModerateMorrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).Compilation only — we have not located an independent source that prints this figure.

Enrofloxacin(Baytril)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO5–10 mg/kgq12h10-14 daysRespiratory infections (Bordetella, Streptococcus)ModerateMeredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).Compilation only — we have not located an independent source that prints this figure.

Trimethoprim-Sulfamethoxazole(Bactrim, TMS)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO15–30 mg/kgq12h10-14 daysRespiratory infectionsModerateMeredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. / 130. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630.Compilation only — we have not located an independent source that prints this figure.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.