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General Anesthesia in Guinea Pigs

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

2 cited drugs treat General Anesthesia in guinea pigs: Alfaxalone Injectable, Propofol Injectable.

Induction and maintenance of general anaesthesia. Injectable induction with ketamine, propofol, alfaxalone, or etomidate; inhalational maintenance with isoflurane or sevoflurane. Species-specific airway anatomy and thermoregulation drive plan choice.

The overview above describes General Anesthesia across species; the citations below are the ExoticRx dose rules scoped to guinea pigs — a reference list, not new species-specific clinical guidance.

Alfaxalone Injectable(Alfaxan)

Neurological
RouteDoseFrequencyDurationIndicationEvidenceSource
IM5 mg/kgOnce (single IM injection)Single doseAnesthesia inductionModerateCarpenter's Exotic Animal Formulary, 6th Ed. | Open-access corroboration: doi:10.1371/journal.pone.0259559 PMID:34780534 — outbred, SPF Dunkin Hartley guinea pigs (38 (26–46) day-old), 5 mg/kg IM (peer_reviewed).

Propofol Injectable(Rapinovet, PropoFlo)

Neurological
RouteDoseFrequencyDurationIndicationEvidenceSource
IV3–5 mg/kgonce, titrate to effectSingle doseAnesthesia inductionWeakCarpenter's Exotic Animal Formulary, 6th ed., Table 9.3 (Chemical Restraint/Anaesthetic Agents Used in Rodents), p.788 — "Propofol 3-5 mg/kg IV130 | Guinea pigs, chinchillas, prairie dogs"; corroborated by Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, Table A.4, p.628 — "Propofol. Guinea Pigs/Chinchillas 3-5 mg/kg IV" (Table 37.2, p.540 gives 3-6 IV) — Carpenter's Exotic Animal Formulary 6th ed, Table 9.3 (Chemical Restraint/Anesthetic Agents Used in Rodents).Compilation only — we have not located an independent source that prints this figure.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.