Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Alfaxalone Injectable is dosed at 5 mg/kg IM Once (single IM injection) in guinea pigs, per Carpenter's Exotic Animal Formulary, 6th Ed. | Open-access corroboration 2026-07-20: doi:10.1371/journal.pone.0259559 PMID:34780534 — outbred, SPF Dunkin Hartley guinea pigs (38 (26–46) day-old), 5 mg/kg IM (peer_reviewed). — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Alfaxalone Injectable is used in guinea pigs for Anesthesia induction. Routes documented in guinea pigs: IM. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Alfaxalone Injectable in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Alfaxan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 5 mg/kg | Once (single IM injection) | Single dose | Anesthesia induction | Moderate | Carpenter's Exotic Animal Formulary, 6th Ed. | Open-access corroboration 2026-07-20: doi:10.1371/journal.pone.0259559 PMID:34780534 — outbred, SPF Dunkin Hartley guinea pigs (38 (26–46) day-old), 5 mg/kg IM (peer_reviewed). — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 40 | IM | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.23 | 40 mg/kg i.m., i.p. |
| 40 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 40 mg/kg IM, IP |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Neuroactive steroid modulating GABA-A receptor. Produces rapid, smooth induction with minimal cardiovascular depression. IM route possible in cats and exotics.
FDA-approved for dogs and cats. IM route useful in fractious cats and exotic species. Apnea possible with rapid IV. Good muscle relaxation. Smooth recovery.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Alfaxalone Injectable dose range in guinea pigs, with cited source references: IM 5 mg/kg Once (single IM injection). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Alfaxalone Injectable in guinea pigs: IM.
Cited course lengths for Alfaxalone Injectable in guinea pigs include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Alfaxalone Injectable is indicated in guinea pigs for: Anesthesia induction.
These are general warnings for Alfaxalone Injectable across species; consult the guinea pig dosing table above for species-specific guidance. FDA-approved for dogs and cats. IM route useful in fractious cats and exotic species. Apnea possible with rapid IV. Good muscle relaxation. Smooth recovery.
Why a species-specific page? Alfaxalone Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.