Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Naloxone is dosed at 0.01–0.1 mg/kg SC, IP not stated in source in guinea pigs, per Henke J, Baumgartner C, Roltgen I, et al. Anaesthesia with midazolam/medetomidine/fentanyl in chinchillas (Chinchilla lanigera) compared to anaesthesia with xylazine/ketamine and medetomidine/ketamine. J Vet Med A Physiol Pathol Clin Med. 2004;51:259-264 / Huerkamp M. Anesthesia and postoperative management of rabbits and pocket pets. In: Bonagura JD, eds. Kirk's Current Veterinary Therapy XII Small Animal Practice; W.B. Saunders, Philadelphia, PA; 1995:1322-1327. / Mayer J. Rodents. In: Carpenter JW, eds. Exotic Animal Formulary, 4th ed., Saunders/Elsevier, St. Louis, MO; 2013:476-516. / Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.787 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.3 (Chemical Restraint/Anesthetic Agents Used in Rodents). Naloxone is used in guinea pigs for Opioid reversal. Routes documented in guinea pigs: SC, IP. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Naloxone in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Narcan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC, IP | 0.01–0.1 mg/kg | not stated in source | Opioid reversal | Moderate | Henke J, Baumgartner C, Roltgen I, et al. Anaesthesia with midazolam/medetomidine/fentanyl in chinchillas (Chinchilla lanigera) compared to anaesthesia with xylazine/ketamine and medetomidine/ketamine. J Vet Med A Physiol Pathol Clin Med. 2004;51:259-264 doi:10.1111/j.1439-0442.2004.00632.x. / Huerkamp M. Anesthesia and postoperative management of rabbits and pocket pets. In: Bonagura JD, eds. Kirk's Current Veterinary Therapy XII Small Animal Practice; W.B. Saunders, Philadelphia, PA; 1995:1322-1327. / Mayer J. Rodents. In: Carpenter JW, eds. Exotic Animal Formulary, 4th ed., Saunders/Elsevier, St. Louis, MO; 2013:476-516. / Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.787 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.3 (Chemical Restraint/Anesthetic Agents Used in Rodents). |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.01–0.1 | SC | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.212 | 0.01-0.1 mg/kg s.c., i.v., i.p. |
| 0.01–0.1 | SC | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 0.01-0.1 mg/kg SC, IP,81,114,122 |
| 0.02 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 0.02 mg/kg/h IV |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Typical range: 0.7–1.2 kg
If provided, volume will be calculated alongside dose.
Reference only. Verify against current literature before clinical use.
Competitive mu, kappa, and delta opioid receptor antagonist. Rapidly reverses opioid-induced respiratory depression, sedation, and hypotension.
Very short duration (30-60 min) — renarcotization risk with long-acting opioids. May precipitate acute withdrawal, pain, and sympathetic surge. Repeat dosing often needed.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Naloxone dose range in guinea pigs, with cited source references: SC, IP 0.01–0.1 mg/kg not stated in source. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Naloxone in guinea pigs: SC, IP.
Naloxone is indicated in guinea pigs for: Opioid reversal.
These are general warnings for Naloxone across species; consult the guinea pig dosing table above for species-specific guidance. Very short duration (30-60 min) — renarcotization risk with long-acting opioids. May precipitate acute withdrawal, pain, and sympathetic surge. Repeat dosing often needed.
Why a species-specific page? Naloxone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.