Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Nalbuphine is dosed at 1–2 mg/kg IM q3h in guinea pigs, per Flecknell PA. Analgesia and post-operative care. Laboratory Animal Anaesthesia; 2016:141-192. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.793 (2026-08-01, PENDING REVIEW) doi:10.1016/b978-0-12-800036-6.00004-1. Nalbuphine is used in guinea pigs for Analgesia (opioid agonist-antagonist). Routes documented in guinea pigs: IM. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Nalbuphine in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nubain
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 1–2 mg/kg | q3h | Analgesia (opioid agonist-antagonist) | Moderate | Flecknell PA. Analgesia and post-operative care. Laboratory Animal Anaesthesia; 2016:141-192. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.793 (2026-08-01, PENDING REVIEW) doi:10.1016/b978-0-12-800036-6.00004-1 |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Kappa opioid receptor agonist and mu opioid receptor antagonist. Provides moderate analgesia with ceiling effect on respiratory depression. Does not increase biliary pressure.
Not a controlled substance despite opioid activity. Ceiling analgesic effect. Will reverse mu-agonist analgesia if given concurrently. Used for moderate pain and to partially reverse mu-agonist side effects.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Nalbuphine dose range in guinea pigs, with cited source references: IM 1–2 mg/kg q3h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Nalbuphine in guinea pigs: IM.
Nalbuphine is indicated in guinea pigs for: Analgesia (opioid agonist-antagonist).
These are general warnings for Nalbuphine across species; consult the guinea pig dosing table above for species-specific guidance. Not a controlled substance despite opioid activity. Ceiling analgesic effect. Will reverse mu-agonist analgesia if given concurrently. Used for moderate pain and to partially reverse mu-agonist side effects.
Why a species-specific page? Nalbuphine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.