Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg
Nalbuphine is dosed at 2–4 mg/kg IM q4h in mice, per 51. Flecknell PA. Analgesia and post-operative care. Laboratory Animal Anaesthesia; 2016:141-192. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.793 (2026-08-01, PENDING REVIEW) doi:10.1016/b978-0-12-800036-6.00004-1. Nalbuphine is used in mice for Analgesia (opioid agonist-antagonist). Routes documented in mice: IM. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 1 cited dose rule for Nalbuphine in mice, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nubain
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 2–4 mg/kg | q4h | Analgesia (opioid agonist-antagonist) | Moderate | 51. Flecknell PA. Analgesia and post-operative care. Laboratory Animal Anaesthesia; 2016:141-192. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.793 (2026-08-01, PENDING REVIEW) doi:10.1016/b978-0-12-800036-6.00004-1 |
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Kappa opioid receptor agonist and mu opioid receptor antagonist. Provides moderate analgesia with ceiling effect on respiratory depression. Does not increase biliary pressure.
Not a controlled substance despite opioid activity. Ceiling analgesic effect. Will reverse mu-agonist analgesia if given concurrently. Used for moderate pain and to partially reverse mu-agonist side effects.
Species-specific contraindications and adverse-reaction reports for mice may differ from canine / feline reference data — consult the primary citations listed with each rule.
Nalbuphine dose range in mice, with cited source references: IM 2–4 mg/kg q4h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Nalbuphine in mice: IM.
Nalbuphine is indicated in mice for: Analgesia (opioid agonist-antagonist).
These are general warnings for Nalbuphine across species; consult the mouse dosing table above for species-specific guidance. Not a controlled substance despite opioid activity. Ceiling analgesic effect. Will reverse mu-agonist analgesia if given concurrently. Used for moderate pain and to partially reverse mu-agonist side effects.
Why a species-specific page? Nalbuphine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mice — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.