Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Propofol Injectable is dosed at 3–5 mg/kg IV once, titrate to effect in guinea pigs, per Carpenter's Exotic Animal Formulary, 6th ed., Table 9.3 (Chemical Restraint/Anaesthetic Agents Used in Rodents), p.788 — "Propofol 3-5 mg/kg IV130 | Guinea pigs, chinchillas, prairie dogs"; corroborated by Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, Table A.4, p.628 (corpus frr p.640) — "Propofol ... Guinea Pigs/Chinchillas 3-5 mg/kg IV" (Table 37.2, p.540 gives 3-6 IV). Propofol Injectable is used in guinea pigs for Anesthesia induction. Routes documented in guinea pigs: IV. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Propofol Injectable in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rapinovet, PropoFlo
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 3–5 mg/kg | once, titrate to effect | Single dose | Anesthesia induction | Weak | Carpenter's Exotic Animal Formulary, 6th ed., Table 9.3 (Chemical Restraint/Anaesthetic Agents Used in Rodents), p.788 — "Propofol 3-5 mg/kg IV130 | Guinea pigs, chinchillas, prairie dogs"; corroborated by Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, Table A.4, p.628 (corpus frr p.640) — "Propofol ... Guinea Pigs/Chinchillas 3-5 mg/kg IV" (Table 37.2, p.540 gives 3-6 IV) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Potentiates GABA-A receptor activity and blocks NMDA receptors. Ultra-short acting IV induction agent. Rapid onset, smooth recovery.
IV only — perivascular injection causes minimal tissue damage (advantage over thiopental). Apnea with rapid injection. Lipid emulsion — strict aseptic handling. Cats: Heinz body anemia with repeated use.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propofol Injectable dose range in guinea pigs, with cited source references: IV 3–5 mg/kg once, titrate to effect. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propofol Injectable in guinea pigs: IV.
Cited course lengths for Propofol Injectable in guinea pigs include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Propofol Injectable is indicated in guinea pigs for: Anesthesia induction.
These are general warnings for Propofol Injectable across species; consult the guinea pig dosing table above for species-specific guidance. IV only — perivascular injection causes minimal tissue damage (advantage over thiopental). Apnea with rapid injection. Lipid emulsion — strict aseptic handling. Cats: Heinz body anemia with repeated use.
Why a species-specific page? Propofol Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.