GI Ulceration in Guinea Pigs

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

3 cited drugs treat GI Ulceration in guinea pigs: Famotidine, Omeprazole, Sucralfate.

Erosive disease of the gastric or duodenal mucosa, often precipitated by NSAID exposure, mast-cell tumour histamine release, or stress in equines. Proton-pump inhibitors and H2 blockers reduce acid secretion; sucralfate provides mucosal protection.

The overview above describes GI Ulceration across species; the citations below are the ExoticRx dose rules scoped to guinea pigs — a reference list, not new species-specific clinical guidance.

Famotidine(Pepcid)

Gastrointestinal

Route	Dose	Frequency	Duration	Indication	Evidence	Source
PO	0.5–1 mg/kg	q12-24h	As needed	Gastric acid reduction	Extrapolated	Carpenter's Exotic Animal Formulary, 6th Ed

Full Famotidine dosing in Guinea Pigs →Calculate for this guinea pig →

Omeprazole(Prilosec, GastroGard)

Gastrointestinal

Route	Dose	Frequency	Duration	Indication	Evidence	Source
PO	0.5–1 mg/kg	q24h	7-14 days	Gastric ulceration	Extrapolated	Carpenter's Exotic Animal Formulary, 6th Ed

Full Omeprazole dosing in Guinea Pigs →Calculate for this guinea pig →

Sucralfate(Carafate)

Gastrointestinal

Route	Dose	Frequency	Duration	Indication	Evidence	Source
PO	25–50 mg/kg	q8-12h	Variable	GI ulceration protection	Weak	Carpenter's Exotic Animal Formulary, 6th Ed
PO	25–50 mg/kg	q8-12h	7-14 days	GI ulceration	Extrapolated	Carpenter's Exotic Animal Formulary, 6th Ed

Full Sucralfate dosing in Guinea Pigs →Calculate for this guinea pig →

All drugs cited for GI Ulceration →All drugs for Guinea Pigs →

Other conditions in Guinea Pigs

Bacterial Infections Respiratory Infections Sedation General Anesthesia Pain Management Coccidiosis Conjunctivitis Endoparasites

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.