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GI Ulceration in Guinea Pigs

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

2 cited drugs treat GI Ulceration in guinea pigs: Famotidine, Sucralfate.

Erosive disease of the gastric or duodenal mucosa, often precipitated by NSAID exposure, mast-cell tumour histamine release, or stress in equines. Proton-pump inhibitors and H2 blockers reduce acid secretion; sucralfate provides mucosal protection.

The overview above describes GI Ulceration across species; the citations below are the ExoticRx dose rules scoped to guinea pigs — a reference list, not new species-specific clinical guidance.

Famotidine(Pepcid)

Gastrointestinal
RouteDoseFrequencyDurationIndicationEvidenceSource
PO0.4–0.5 mg/kgq24hAs neededGastric acid reductionExtrapolatedCarpenter's Exotic Animal Formulary, 6th ed., Table 9.7 Miscellaneous Agents Used in Rodents, p.800. Corroborated by BSAVA Part B p.127 ('Guinea pigs: 0.4 mg/kg p.o., s.c. q24h') and FRR 4th ed. Appendix Table A.5 p.629 (Guinea Pigs/Chinchillas: 0.4-0.5 mg/kg PO, SC q24h) — Carpenter's Exotic Animal Formulary 6th ed, Table 9.7 (Miscellaneous Agents Used in Rodents).Compilation only — we have not located an independent source that prints this figure.

Sucralfate(Carafate)

Gastrointestinal
RouteDoseFrequencyDurationIndicationEvidenceSource
PO25–50 mg/kgq8-12h7-14 daysGI ulcerationExtrapolatedMorrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Carpenter's Exotic Animal Formulary 6th ed, Table 9.7 (Miscellaneous Agents Used in Rodents).Compilation only — we have not located an independent source that prints this figure.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.