Reptile · Python regius · typical adult weight 1.00–2.00 kg
Acepromazine is dosed at 0.05–0.25 mg/kg IM not stated in source in ball pythons, per Klaphake E, Gibbons PM, Sladky KK, et al. Reptiles. In: Carpenter JW, eds. Exotic Animal Formulary, 5th ed., Elsevier, St. Louis, MO; 2018:81-166. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.234 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.5 (Chemical Restraint/Anesthetic Agents Used in Reptiles.a). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Acepromazine is used in ball pythons for Preanesthetic sedation. Routes documented in ball pythons: IM. A typical adult ball python weighs 1.00–2.00 kg. ExoticRx lists 1 cited dose rule for Acepromazine in ball pythons, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: PromAce, Atravet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.05–0.25 mg/kg | not stated in source | Preanesthetic sedation |
| Klaphake E, Gibbons PM, Sladky KK, et al. Reptiles. In: Carpenter JW, eds. Exotic Animal Formulary, 5th ed., Elsevier, St. Louis, MO; 2018:81-166. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.234 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.5 (Chemical Restraint/Anesthetic Agents Used in Reptiles.a). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.1–0.5 | IM | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.16 | 0.1-0.5 mg/kg i.m. a |
| 0.1–0.5 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.1-0.5 mg/kg IM,362 |
| 0.05–0.25 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.05-0.25 mg/kg IM |
| 0.5 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed |
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These ranges are per kg. Enter your ball python's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Blocks dopamine D2 receptors in the CNS, producing sedation and anxiolysis. Also has alpha-1 adrenergic blocking properties causing vasodilation.
Hypotension (alpha blockade) — avoid in hypovolemic patients. DO NOT use in giant breeds (boxers extremely sensitive — exaggerated hypotension). No analgesic effect. Lowers seizure threshold. Not reversible.
Species-specific contraindications and adverse-reaction reports for ball pythons may differ from canine / feline reference data — consult the primary citations listed with each rule.
Acepromazine dose range in ball pythons, with cited source references: IM 0.05–0.25 mg/kg not stated in source. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Acepromazine in ball pythons: IM.
Acepromazine is indicated in ball pythons for: Preanesthetic sedation.
These are general warnings for Acepromazine across species; consult the ball python dosing table above for species-specific guidance. Hypotension (alpha blockade) — avoid in hypovolemic patients. DO NOT use in giant breeds (boxers extremely sensitive — exaggerated hypotension). No analgesic effect. Lowers seizure threshold. Not reversible.
Why a species-specific page? Acepromazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in ball pythons — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| (A) 0.5 mg/kg IM + (P) 5 mg/kg IV; (A) 0 kg IM + (P) 10 mg/kg IV5 .5 mg/ Giant Amazon pond turtles/sedation with both protocols, longer duration with higher propofol dosage |
| 5 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | (A) 0.5 mg/kg IM + (P) 5 mg/kg IV; (A) 0 kg IM + (P) 10 mg/kg IV5 .5 mg/ Giant Amazon pond turtles/sedation with both protocols, longer duration with higher propofol dosage |
| 10 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | (A) 0.5 mg/kg IM + (P) 5 mg/kg IV; (A) 0 kg IM + (P) 10 mg/kg IV5 .5 mg/ Giant Amazon pond turtles/sedation with both protocols, longer duration with higher propofol dosage |
| 0.05–0.25 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 0.05-0.25 mg/kg IM Most species/can be used as a preanesthetic with ketamine |
| 0.1–0.5 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 0.1-0.5 mg/kg IM229,259 Most species/preanesthetic; reduce by 50% if used with barbiturates |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.