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Acetylcysteine for Guinea Pig

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

Acetylcysteine is used in guinea pig for Respiratory mucus clearance. Routes documented in guinea pig: Nebulization. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Acetylcysteine in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Mucomyst, ACC

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
Nebulization50 mg/ml nebulizedq12h3-5 daysRespiratory mucus clearanceWeakCarpenter's Exotic Animal Formulary, 6th Ed

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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Breaks disulfide bonds in mucus glycoproteins reducing viscosity (mucolytic). Also a glutathione precursor providing hepatoprotection (acetaminophen antidote).

Side effects & warnings

Dual role: mucolytic (nebulized/oral) and acetaminophen antidote (IV/oral). Bronchospasm possible with nebulization — pretreat with bronchodilator. Foul smell.

Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Respiratory drugs with guinea pig dosing

Acetylcysteine dosing in other species

Why a species-specific page? Acetylcysteine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.