Afoxolaner for Corn Snakes
Reptile · Pantherophis guttatus · typical adult weight 0.20–0.90 kg
Afoxolaner is dosed at 2.5 mg/kg PO single administration in corn snakes, per Afoxolaner (NexGard®) in pet snakes for the treatment and control of Ophionyssus natricis (Mesostigmata: Macronyssidae). Parasites & Vectors, 2022. DOI 10.1186/s13071-022-05611-1; PMID 36609309; PMCID PMC9825044. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC9825044/. Afoxolaner is used in corn snakes for Treatment and control of Ophionyssus natricis (snake mite) infestation. Routes documented in corn snakes: PO. A typical adult corn snake weighs 0.20–0.90 kg. ExoticRx lists 1 cited dose rule for Afoxolaner in corn snakes, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: NexGard
Dose ranges
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 2.5 mg/kg | single administration | Treatment and control of Ophionyssus natricis (snake mite) infestation | Weak | Afoxolaner (NexGard®) in pet snakes for the treatment and control of Ophionyssus natricis (Mesostigmata: Macronyssidae). Parasites & Vectors, 2022. DOI 10.1186/s13071-022-05611-1; PMID 36609309; PMCID PMC9825044. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC9825044/ |
Need the exact dose for your patient?
These ranges are per kg. Enter your corn snake's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Isoxazoline ectoparasiticide blocking GABA and glutamate-gated chloride channels in arthropods. Monthly flea and tick protection.
Side effects & warnings
FDA-approved for dogs. Seizure potential in dogs with neurologic history. Not for use in puppies <8 weeks or <1.8kg. Dogs only (not cats).
Species-specific contraindications and adverse-reaction reports for corn snakes may differ from canine / feline reference data — consult the primary citations listed with each rule.
Frequently asked questions
What is the dose of Afoxolaner for Corn Snakes?
Afoxolaner dose range in corn snakes, with cited source references: PO 2.5 mg/kg single administration.
How is Afoxolaner administered in Corn Snakes?
Documented routes for Afoxolaner in corn snakes: PO.
What conditions does Afoxolaner treat in Corn Snakes?
Afoxolaner is indicated in corn snakes for: Treatment and control of Ophionyssus natricis (snake mite) infestation.
What are the side effects of Afoxolaner in Corn Snakes?
These are general warnings for Afoxolaner across species; consult the corn snake dosing table above for species-specific guidance. FDA-approved for dogs. Seizure potential in dogs with neurologic history. Not for use in puppies <8 weeks or <1.8kg. Dogs only (not cats).
Afoxolaner dosing in other species
Why a species-specific page? Afoxolaner pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in corn snakes — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.