Reptile · Lampropeltis getula · typical adult weight 0.18–2.27 kg
Afoxolaner is dosed at 2.5 mg/kg PO single dose in kingsnakes, per Mendoza-Roldan JA, Napoli E, Perles L, et al. Afoxolaner (NexGard) in pet snakes for the treatment and control of Ophionyssus natricis (Mesostigmata: Macronyssidae). Parasit Vectors. 2023;16(1):6. doi:10.1186/s13071-022-05611-1 https://europepmc.org/article/PMC/PMC9825044. Afoxolaner is used in kingsnakes for Snake mite (Ophionyssus natricis) infestation. Routes documented in kingsnakes: PO. A typical adult kingsnake weighs 0.18–2.27 kg. ExoticRx lists 1 cited dose rule for Afoxolaner in kingsnakes, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: NexGard
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 2.5 mg/kg | single dose | Snake mite (Ophionyssus natricis) infestation | Moderate | Mendoza-Roldan JA, Napoli E, Perles L, et al. Afoxolaner (NexGard) in pet snakes for the treatment and control of Ophionyssus natricis (Mesostigmata: Macronyssidae). Parasit Vectors. 2023;16(1):6. doi:10.1186/s13071-022-05611-1 https://europepmc.org/article/PMC/PMC9825044 |
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These ranges are per kg. Enter your kingsnake's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Isoxazoline ectoparasiticide blocking GABA and glutamate-gated chloride channels in arthropods. Monthly flea and tick protection.
FDA-approved for dogs. Seizure potential in dogs with neurologic history. Not for use in puppies <8 weeks or <1.8kg. Dogs only (not cats).
Species-specific contraindications and adverse-reaction reports for kingsnakes may differ from canine / feline reference data — consult the primary citations listed with each rule.
Afoxolaner dose range in kingsnakes, with cited source references: PO 2.5 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Afoxolaner in kingsnakes: PO.
Afoxolaner is indicated in kingsnakes for: Snake mite (Ophionyssus natricis) infestation.
These are general warnings for Afoxolaner across species; consult the kingsnake dosing table above for species-specific guidance. FDA-approved for dogs. Seizure potential in dogs with neurologic history. Not for use in puppies <8 weeks or <1.8kg. Dogs only (not cats).
Why a species-specific page? Afoxolaner pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in kingsnakes — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.