Amphibian · Anaxyrus houstonensis · typical adult weight 0.03–0.09 kg
Atipamezole is dosed at 1 mg/kg SC Single reversal dose, 45 minutes after induction in houston toads, per Lang M, Freeman K, Griffioen J, Cannizzo S, Delaney MA. Comparison of Subcutaneous Alfaxalone and Subcutaneous Alfaxalone-Dexmedetomidine for Sedation in the Houston Toad (Anaxyrus houstonensis). J Zoo Wildl Med. 2024;55(1). doi:10.1638/2023-0013 https://bioone.org/journals/journal-of-zoo-and-wildlife-medicine/volume-55/issue-1/2023-0013/COMPARISON-OF-SUBCUTANEOUS-ALFAXALONE-AND-SUBCUTANEOUS-ALFAXALONEDEXMEDETOMIDINE-FOR-SEDATION-IN/10.1638/2023-0013.full. Atipamezole is used in houston toads for Reversal of dexmedetomidine sedation. Routes documented in houston toads: SC. A typical adult houston toad weighs 0.03–0.09 kg. ExoticRx lists 1 cited dose rule for Atipamezole in houston toads, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 1 mg/kg | Single reversal dose, 45 minutes after induction | Reversal of dexmedetomidine sedation | Moderate | Lang M, Freeman K, Griffioen J, Cannizzo S, Delaney MA. Comparison of Subcutaneous Alfaxalone and Subcutaneous Alfaxalone-Dexmedetomidine for Sedation in the Houston Toad (Anaxyrus houstonensis). J Zoo Wildl Med. 2024;55(1). doi:10.1638/2023-0013 https://bioone.org/journals/journal-of-zoo-and-wildlife-medicine/volume-55/issue-1/2023-0013/COMPARISON-OF-SUBCUTANEOUS-ALFAXALONE-AND-SUBCUTANEOUS-ALFAXALONEDEXMEDETOMIDINE-FOR-SEDATION-IN/10.1638/2023-0013.full |
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These ranges are per kg. Enter your houston toad's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for houston toads may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose range in houston toads, with cited source references: SC 1 mg/kg Single reversal dose, 45 minutes after induction. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in houston toads: SC.
Atipamezole is indicated in houston toads for: Reversal of dexmedetomidine sedation.
These are general warnings for Atipamezole across species; consult the houston toad dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in houston toads — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.