ExoticRx · exoticrx.com/drugs/cinacalcet
Sensipar
Allosteric activator of the calcium-sensing receptor (CaSR) on parathyroid chief cells, increasing receptor sensitivity to calcium and reducing PTH secretion.
Hypocalcemia risk — monitor ionized calcium. Nausea and vomiting common. Investigational for primary hyperparathyroidism in dogs.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–3 mg/kg | q12-24h | Weak | JVIM 2019; Veterinary Endocrinology Literature |
| Cat (Domestic) | PO | 1–3 mg/kg | q12-24h | Extrapolated | JVIM 2019; Veterinary Endocrinology Literature |
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