ExoticRx · exoticrx.com/drugs/closantel
US brand names:Flukiver, Seponver
Uncouples oxidative phosphorylation in parasites. Active against immature and adult Fasciola hepatica and Haemonchus.
TOXIC to dogs — do not use. Narrow safety margin in sheep/goats. Blindness reported with overdose. Long withdrawal times.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | TOXIC TO DOGS | NOT RECOMMENDED | Anecdotal | Entee, K.M., Grauwels, M., Clerc, B., et al. (1995) Closantel intoxication in a dog. Veterinary and Human Toxicology, 37, 234-236. — Verified against Veterinary Ophthalmology (Gelatt), 6th Ed, p.1650 (2026-08-01). |
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