Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Diazoxide is dosed at 5–25 mg/kg PO q12h in guinea pigs, per Hess LR, Ravich ML, Reavill DR. Diagnosis and treatment of an insulinoma in a guinea pig (Cavia porcellus). J Am Vet Med Assoc. 2013;242:522-526. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.799 (2026-08-01, PENDING REVIEW). Diazoxide is used in guinea pigs for Insulinoma. Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Diazoxide in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Proglycem
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 5–25 mg/kg | q12h | Insulinoma | Weak | Hess LR, Ravich ML, Reavill DR. Diagnosis and treatment of an insulinoma in a guinea pig (Cavia porcellus). J Am Vet Med Assoc. 2013;242:522-526. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.799 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Opens KATP channels in pancreatic beta cells, inhibiting insulin secretion. Also has extrapancreatic hyperglycemic effects.
Used for insulinoma management (dogs). GI upset, anorexia, hypotension. Sodium and fluid retention (may need diuretic). Monitor blood glucose. Expensive.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Diazoxide dose range in guinea pigs, with cited source references: PO 5–25 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Diazoxide in guinea pigs: PO.
Diazoxide is indicated in guinea pigs for: Insulinoma.
These are general warnings for Diazoxide across species; consult the guinea pig dosing table above for species-specific guidance. Used for insulinoma management (dogs). GI upset, anorexia, hypotension. Sodium and fluid retention (may need diuretic). Monitor blood glucose. Expensive.
Why a species-specific page? Diazoxide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.