ExoticRx · exoticrx.com/drugs/diazoxide
Diazoxide
Proglycem
Drug Class
Routes
Indications
Mechanism of Action
Opens KATP channels in pancreatic beta cells, inhibiting insulin secretion. Also has extrapancreatic hyperglycemic effects.
Side effects & warnings
Used for insulinoma management (dogs). GI upset, anorexia, hypotension. Sodium and fluid retention (may need diuretic). Monitor blood glucose. Expensive.
Species with Diazoxide dosing data (1 dose rule)
Species references:All Dog (Domestic) drugs
Evidence levels across 1 dose rule
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (1 of 1 cited rule)
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5–30 mg/kg | q12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.