ExoticRx · exoticrx.com/drugs/diazoxide
US brand names:Proglycem
Diazoxide is dosed at 5–30 mg/kg PO q12h in ferrets, per Marini RP, Ryden EB, Rosenblad WD, et al. Functional islet cell tumor in six ferrets. J Am Vet Med Assoc. 1993;202:430-433. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.949 doi:10.2460/javma.1993.202.03.430 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.8 (Endocrine and Reproductive Disease Agents Used in Ferrets). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
Opens KATP channels in pancreatic beta cells, inhibiting insulin secretion. Also has extrapancreatic hyperglycemic effects.
Used for insulinoma management (dogs). GI upset, anorexia, hypotension. Sodium and fluid retention (may need diuretic). Monitor blood glucose. Expensive.
Species references:All Dog (Domestic) drugsAll Ferret drugsAll Guinea Pig drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5–30 mg/kg | q12h | Moderate | Nelson RW. Chapter 9: Beta-Cell Neoplasia: Insulinoma. In: Feldman EC, Nelson RW, Reusch CE, Scott-Moncrieff JCR, Behrend EN, eds. Canine and Feline Endocrinology. 4th ed. Elsevier Saunders; 2015:348-375. doi:10.1016/b978-1-4557-4456-5.00009-2 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.410 (2026-08-01). — Plumb's 10th ed (held) printed p.382, Diazoxide monograph spanning p.382-383; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.